Safety of Platelet and Plasma Transfusions in the COVID-19 Era By September 2022, 96% of U.S. blood donors had antibodies to SARS-CoV-2 due to infection and/or vaccination. Some patient advocacy… December 13, 2023
COVID-19 Convalescent Plasma Reduces Mortality for Patients with Acute Respiratory Distress Syndrome COVID-19 mortality among patients in the intensive care unit receiving mechanical ventilation is around 45%, and little data exists on… November 8, 2023
Recombinant von Willebrand Factor and Tranexamic Acid for Menstruating Women with von Willebrand Disease Von Willebrand disease is an inherited bleeding disorder affecting about 0.1% of the population. Von Willebrand disease is caused by… September 13, 2023
Concizumab Lowers Rate of Bleeding in Hemophilia Patients with Inhibitors While current guidelines for treating patients with hemophilia A or B recommend intravenous factor VIII or IX concentrates, many patients… September 6, 2023
Prothrombin Complex Concentrate Increases Risk of Thromboembolic Events in Trauma Patients Four-factor prothrombin complex concentrate (4F-PCC) is a lyophilized concentrate of coagulation factors that is commonly used for urgent reversal of… March 29, 2023
Thromboelastometry and Clinical Guidance for Fibrinogen Infusions during Liver Transplantation Thromboelastometry provides individualized measures of clot kinetics and structure, and has played an increasingly important role in the management of… February 8, 2023
Plasmapheresis Associated with Reduced Mortality Among Patients with Severe COVID-19 Over 6 million people have died due to COVID-19 worldwide since the start of the pandemic. Several comorbidities are associated… January 18, 2023
COVID-19 Convalescent Plasma Improves Outcomes for Cancer Patients Standard COVID-19 therapies and vaccines have limited effectiveness in patients with impaired humoral immune responses, and these patients have a… January 10, 2023
Cryopreserved Platelets for Functional Assays Both heparin-induced thrombocytopenia (HIT) and vaccine-induced immune thrombotic thrombocytopenia (VITT) are rare but serious drug reactions. HIT and VITT are… January 3, 2023
Prothrombin Complex Concentrate Reduces RBC Transfusions during Cardiac Surgery Over one million people undergo complex cardiac surgeries worldwide each year. Cardiac surgeries carry a considerable risk of postoperative bleeding… December 21, 2022