High-Titer Convalescent Plasma Increases Long-Term Survival for Patients with Severe COVID-19 Randomized controlled clinical trials have evaluated the safety and efficacy of COVID-19 convalescent plasma (CCP) and found high-titer CCP reduced… November 16, 2022
Prothrombin Complex Concentrate for Complex Cardiac Surgery Patients Many cardiopulmonary bypass surgery patients with coagulopathy and bleeding require post-operative plasma transfusions. Instead of plasma, the off-label use of… July 14, 2022
Tranexamic Acid in Noncardiac Surgeries Large randomized clinical trials have shown that tranexamic acid safely reduces bleeding in patients undergoing cardiac surgery or cesarean sections,… May 3, 2022
AABB Issues COVID-19 Convalescent Plasma Clinical Practice Guidelines The use of COVID-19 convalescent plasma (CCP) has been highly controversial since the beginning of the pandemic. With the Food… April 12, 2022
Covid-19 Convalescent Plasma Neutralizes Variants of Concern Including Omicron Recent omicron variants of the SARS-CoV-2 virus have at least 32 changes in the spike protein relative to the original… March 9, 2022
Hospitalized COVID-19 Patients with Early Disease and Preexisting Conditions May Benefit from Convalescent Plasma Understanding which patients with COVID-19 benefit the most from COVID-19 convalescent plasma (CCP) may help determine how convalescent plasma may… February 2, 2022
Outpatient COVID-19 Convalescent Plasma Reduces Hospitalizations While more than 500,000 units of COVID-19 convalescent plasma (CCP) have been transfused in the United States alone, the use… December 21, 2021
Cold-Stored Group O Whole Blood Use in Severely Injured Patients Trauma patients have a severe risk of hemorrhagic shock, and managing their platelet count is crucial for their survival. In… December 14, 2021
FDA Update about Bacterial Contamination of Platelets The United Stated Food and Drug Administration (FDA) issued guidance to reduce the risk of septic transfusion reactions associated with… December 8, 2021
RBC and Plasma Transfusions Decreased in the U.S. (2015-2018) Blood transfusions are one of the most common medical procedures in hospitalized patients, and robust data from randomized clinical trials… September 28, 2021