Long-term Survival of Severe Trauma Patients Treated with Tranexamic Acid Globally, trauma is the leading cause of death for young people. In 2011, the World Health Organization added tranexamic acid… June 21, 2023
Trauma Endotypes and Transfusion Resuscitation Strategies In 2015 results from the Pragmatic, Randomized Optimal Platelet and Plasma Ratios (PROPPR) trial suggested that a 1:1:1 ratio of… May 24, 2023
Prothrombin Complex Concentrate Increases Risk of Thromboembolic Events in Trauma Patients Four-factor prothrombin complex concentrate (4F-PCC) is a lyophilized concentrate of coagulation factors that is commonly used for urgent reversal of… March 29, 2023
Acute Normovolemic Hemodilution Reduces Transfusions in Patients Undergoing Cardiac Surgery Approximately one to two million cardiac surgery operations are performed worldwide each year accounting for about 80% of all surgical… March 15, 2023
Increased Blood Use and Cost for Emergency Transfusions with Whole Blood Compared to Packed Red Blood Cells In the past two decades, a growing number of hospitals have started using whole blood to treat trauma patients and… February 16, 2023
Whole Blood and Survival in Adult Trauma Patients While blood component transfusions have been the standard of care for the past four decades, there is increasing interest in… January 25, 2023
Plasmapheresis Associated with Reduced Mortality Among Patients with Severe COVID-19 Over 6 million people have died due to COVID-19 worldwide since the start of the pandemic. Several comorbidities are associated… January 18, 2023
Sickle Cell Trait Testing of RBC Units While individuals with the sickle cell trait (SCT) have a single allele of hemoglobin S (HbS) and are eligible blood… December 27, 2022
HbS Promotes Proinflammatory Cytokine Production in Sickle Cell Disease Unlike patients with intravascular hemolysis without sickle cell disease (SCD) or those with β-thalassemia, patients with SCD have elevated baseline… November 9, 2022
Transfusion Thresholds for Patients Receiving ECMO Venovenous extracorporeal membrane oxygenation (ECMO) can be used to help provide respiratory support to patients with severe acute respiratory distress… November 2, 2022