Risk of Graft-Versus-Host Disease Dependent on Apheresis Device Used to Collect Allogeneic Stem Cells The composition of stem cell grafts can affect the risk of graft-versus-host disease (GvHD), time to engraftment, and relapse for… June 13, 2018
Gene Therapy for β-Thalassemia Patients who Are Transfusion Dependent β-thalassemia is one of the most common genetic diseases—especially in North Africa, the Middle East and Asia. About 60-80% of… April 25, 2018
Successful Treatment of Refractory B-cell Lymphomas with CAR T-Cell Therapy Chimeric antigen receptor (CAR) T-cell therapy has been shown to successfully treat refractory B-cell lymphomas. Two new studies published in… January 3, 2018
Gene Therapy for Hemophilia A Patients Successful Gene therapy using adeno-associated viral (AAV) vectors has been successfully used to treat patients with hemophilia B. Gene therapy for… December 28, 2017
Potential Screening for Cytomegalovirus among Cord Blood Donors Infection with cytomegalovirus (CMV) can cause severe complications for hematopoietic stem cell transplant patients. In addition to screening for maternal… November 9, 2017
FDA Approves CAR-T Gene Therapy for Acute Lymphoblastic Leukemia With the FDA approval of the first gene therapy, or a nucleic acid drug, we have entered a new era… September 7, 2017
Apheresis Lymphocyte Collections for CAR-T Cell Production Usually Well Tolerated By Cancer Patients Production of chimeric antigen receptor (CAR) T-cells involve genetically modifying the patient’s own T-cells, and these cells have been shown… May 17, 2017
Improving Peripheral Blood Stem Cell Collection for Autologous Stem Cell Transplantation The City of Hope National Medical Center in California performs nearly 400 autologous stem cell transplants (ASCT) per year using… January 11, 2017
Mutating Haematopoietic Stem Cells May Cure Sickle Cell Disease Sickle cell disease and β-thalassaemia are caused by mutations in the β -globin gene. Previous studies have shown that transplants… November 16, 2016
Cord Blood Transplants Beneficial When Matched Donors Cannot Be Found The majority of patients in need of allogeneic hematopoietic cell-transplants do not have HLA-matched donors available. Researchers recently performed a… September 14, 2016
Cell Therapy