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Transfusion Transmitted Infections

RBC Exchange Transfusion for Patients with Severe Babesiosis

Babesiosis is a tick-borne disease primarily transmitted by the intraerythrocytic protozoa Babesia microti in the U.S., which causes malaria-like symptoms…

April 14, 2026

Oropouche Virus RNA Detected in Blood Donors in Brazil

The oropouche virus (OROV) is primarily transmitted by Culicoides paraensis midges but transmission also occurs by some Culex mosquitoes and…

April 8, 2026

Pathogen Reduction of Platelets and Risk of Transfusion-Transmitted Bacterial Infections

Pathogen reduction (PR) systems decrease the risk of transfusion-transmitted infections (TTI), and many blood centers use PR to treat platelets…

March 18, 2026

Locally Transmitted Malaria in the United States

Currently, half of the world’s population is at risk for malaria. Although malaria was endemic across the southern region of…

October 15, 2025

Transfusion-related Alpha-Gal Syndrome

Alpha-gal syndrome (AGS), first described in 2009, is associated with a tick bite in which exposed individuals develop IgE antibodies…

August 13, 2025

Syphilis Infections Among US Blood Donors

Syphilis is a sexually transmitted bacterial infection that may also be transmitted by transfusion.  Active cases of syphilis are increasing…

July 10, 2025

Babesia Infection Reduces Red Cell Deformability

The United States reports the highest number of Babesia infections globally. Babesia, a tick-borne pathogen related to the malaria parasite,…

May 14, 2025

No Transfusion-Transmission of Classic Creutzfeldt-Jakob Disease

Classic Creutzfeldt-Jakob disease (CJD) is a rare and fatal neurodegenerative spongiform encephalopathy caused by prions (i.e., misfolded proteins). First recognized…

July 17, 2024

National Surveillance for Unknown Transfusion-Transmitted Infections

The prevention of transfusion-transmitted infections (TTI) is largely based on recruiting donors at low risk of being infected with a…

March 13, 2024

A Possible Link between RBC Transfusions and Brain Amyloidosis?

Cerebral amyloid angiopathy (CAA) has multiple etiologies but is characterized by deposits of misfolded amyloid β peptides and is the…

September 20, 2023

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  • RBC Exchange Transfusion for Patients with Severe Babesiosis

  • Oropouche Virus RNA Detected in Blood Donors in Brazil

  • Intravenous Iron More Effective than Oral to Treat Anemia in Postpartum Women

  • Prehospital Whole Blood is Not Superior to Blood Components for Trauma Patients

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