CHIPS Trial Comparing Cold and Room-Temperature Stored Platelets for Cardiac Surgery Patients Over 50 years ago room-temperature stored platelets (RTPs) were shown to have increased platelet recovery and survival compared to cold-stored… August 26, 2026
Neonatal Platelets Limit Adaptive Immune Response The neonatal immune system is adapted to address ongoing tissue development and microbiome colonization. In addition to maternal antibodies, myeloid-derived… August 18, 2026
Freeze-Dried Platelets Reduce Blood Brain Barrier Permeability and Intercranial Hemorrhage in Mice with Traumatic Brain Injury Traumatic brain injury (TBI) is fatal in >30% of cases. While plasma transfusions have been shown to help reduce TBI… July 8, 2026
Donor, Storage, and Processing Characteristics Associated with Platelet Transfusion Outcomes Platelet transfusions are critical to many patients such as those with thrombocytopenia, bleeding patients, and patients at risk of bleeding…. May 5, 2026
Pathogen Reduction of Platelets and Risk of Transfusion-Transmitted Bacterial Infections Pathogen reduction (PR) systems decrease the risk of transfusion-transmitted infections (TTI), and many blood centers use PR to treat platelets… March 18, 2026
Tranexamic Acid for Patients with Hematological Disorders Patients with hematological disorders are often thrombocytopenic due to the pathology of their disease and/or treatment. Platelet transfusions, used both… February 26, 2026
Cryopreserved vs. Standard Platelets for Surgical Bleeding Hospitals in low- and middle-income countries, as well as military and rural hospitals in high-income countries, lack reliable access to… December 17, 2025
Global Platelet Transfusion Practices for Patients in the ICU Platelet transfusion rates for patients in the ICU range from 5% to 15%, but guidelines are primarily based on observational… October 8, 2025
Personalized Prediction Model of Prophylactic Platelet Transfusions for Preterm Infants International transfusion guidelines based on one large randomized controlled trial for preterm infants with severe thrombocytopenia (platelet count < 50… September 24, 2025
Tranexamic Acid Does Not Reduce Bleeding or Transfusions in Patients with Hematological Malignancies Prophylactic platelet transfusions are common for patients with hematological malignancies and severe hypoproliferative thrombocytopenia. Tranexamic acid, an antifibrinolytic drug, has… January 30, 2025
Platelet Transfusion