RBCs with Reduced Deformability are Removed from Circulation RBCs, with a diameter of 8 µm, must squeeze through narrow microvascular spaces and endothelial clefts just 1 to 2.5… July 2, 2025
Acute Normovolemic Hemodilution Does Not Reduce RBC Transfusions Globally, over two million individuals undergo cardiac surgery annually, and about one third receive at least one unit of allogeneic… June 18, 2025
Anemia Treatment Bundle Improves Hemoglobin Recovery after Critical Illness Very few studies have examined how anemia management strategies affect post-hospitalization outcomes for critically ill patients. A recent randomized controlled… April 16, 2025
Blood Collection and Transfusions Stable in the U.S. According to the 2023 U.S. National Blood Collection and Utilization Survey (NBCUS), blood transfusions have stabilized following a sharp decline… March 26, 2025
Sovleplenib to Treat Warm Autoimmune Hemolytic Anemia Warm autoimmune hemolytic anemia is a rare and serious disorder with limited treatment options; RBC transfusions can provide short term… March 12, 2025
Donor Age, Not Donor Sex, Is the Primary Factor Influencing RBC Deformability RBC deformability—the ability to alter shape and squeeze through capillaries and other microvascular tissues—is essential for oxygen delivery to tissues… March 5, 2025
Using Machine Learning Models to Predict the Likelihood of a Transfusion Over 85 million units of RBCs are transfused annually worldwide, and the decision to transfuse is usually based on a… February 26, 2025
Antibodies to Amustaline/Glutathione Pathogen Reduced RBCs While the U.S. FDA has approved the use of pathogen reduction (PR) technologies for platelets and plasma, it has not… February 12, 2025
A New, Simple Proxy to Measure Oxygen Unloading and the Quality of Stored Blood The functional quality of transfused blood depends upon oxygen delivery to the tissues. Oxygen carrying capacity is easily and routinely… January 16, 2025
Hypovolemic Phlebotomy Reduces Transfusions During Liver Surgery About 15% to 20% of patients undergoing liver resections require RBC transfusions. Current guidelines propose a number of options to… January 8, 2025