Prothrombin Complex Concentrate Increases Risk of Thromboembolic Events in Trauma Patients Four-factor prothrombin complex concentrate (4F-PCC) is a lyophilized concentrate of coagulation factors that is commonly used for urgent reversal of… March 29, 2023
Thromboelastometry and Clinical Guidance for Fibrinogen Infusions during Liver Transplantation Thromboelastometry provides individualized measures of clot kinetics and structure, and has played an increasingly important role in the management of… February 8, 2023
Plasmapheresis Associated with Reduced Mortality Among Patients with Severe COVID-19 Over 6 million people have died due to COVID-19 worldwide since the start of the pandemic. Several comorbidities are associated… January 18, 2023
COVID-19 Convalescent Plasma Improves Outcomes for Cancer Patients Standard COVID-19 therapies and vaccines have limited effectiveness in patients with impaired humoral immune responses, and these patients have a… January 10, 2023
Cryopreserved Platelets for Functional Assays Both heparin-induced thrombocytopenia (HIT) and vaccine-induced immune thrombotic thrombocytopenia (VITT) are rare but serious drug reactions. HIT and VITT are… January 3, 2023
Prothrombin Complex Concentrate Reduces RBC Transfusions during Cardiac Surgery Over one million people undergo complex cardiac surgeries worldwide each year. Cardiac surgeries carry a considerable risk of postoperative bleeding… December 21, 2022
High-Titer Convalescent Plasma Increases Long-Term Survival for Patients with Severe COVID-19 Randomized controlled clinical trials have evaluated the safety and efficacy of COVID-19 convalescent plasma (CCP) and found high-titer CCP reduced… November 16, 2022
Prothrombin Complex Concentrate for Complex Cardiac Surgery Patients Many cardiopulmonary bypass surgery patients with coagulopathy and bleeding require post-operative plasma transfusions. Instead of plasma, the off-label use of… July 14, 2022
Tranexamic Acid in Noncardiac Surgeries Large randomized clinical trials have shown that tranexamic acid safely reduces bleeding in patients undergoing cardiac surgery or cesarean sections,… May 3, 2022
AABB Issues COVID-19 Convalescent Plasma Clinical Practice Guidelines The use of COVID-19 convalescent plasma (CCP) has been highly controversial since the beginning of the pandemic. With the Food… April 12, 2022
Coagulation & Plasma Transfusion