HLA Induced Refractoriness to Platelet Transfusions Platelet transfusion refractoriness (PTR) is usually caused by non-immune platelet consumption but can also be caused by immune-mediated platelet destruction. … June 16, 2021
High Titer Convalescent Plasma Does Not Improve Survival of Hospitalized Patients with COVID-19 With few treatment options, more than 500,000 patients with COVID-19 were transfused with convalescent plasma in the United States. Observational… May 26, 2021
ABO-incompatible Platelet Transfusions and Platelet Recovery in Patients with Intracerebral Hemorrhage Historically, standard practice has been to provide ABO-compatible platelets when possible. However, since hemolysis is rare after single platelet transfusions… May 18, 2021
Tranexamic Acid To Reduce Blood Loss after Cesarean Delivery Tranexamic acid is a common antifibrinolytic drug used to prevent blood loss during surgeries and treat heavy menstrual cycles. Several… May 5, 2021
Updated Guidance for COVID-19 Convalescent Plasma Use from the FDA and AABB With a lack of effective treatments for COVID-19, the U.S. FDA issued Emergency Use Authorization to use convalescent plasma to… February 17, 2021
Early Convalescent Plasma Therapy Helps Prevent Severe COVID-19 COVID-19 convalescent plasma administered late in the course of disease has not shown clear benefits, but some studies suggest that… January 12, 2021
Cochrane Living Systematic Review: More Data Needed to Determine Efficacy of COVID-19 Convalescent Plasma Researchers from the Cochrane Library are performing monthly systematic reviews to evaluate the current data on the effectiveness of COVID-19… October 28, 2020
COVID-19 Convalescent Plasma Provides More than Neutralizing Antibodies With few drugs to combat SARS-CoV-2 infections and the approval from the U.S. FDA for Emergency Use Authorization of COVID-19… September 30, 2020
NIH Urges Randomized Controlled Trials for COVID-19 Convalescent Plasma On September 1, 2020, shortly after the U.S. Food and Drug’s Emergency Use Authorization (EUA) for the use of COVID-19… September 9, 2020
FDA Issues Emergency Use Authorization for COVID-19 Convalescent Plasma To increase access to COVID-19 convalescent plasma (CCP) use, President Trump, in conjunction with the U.S. FDA, announced Emergency Use… August 25, 2020