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Coagulation & Plasma Transfusion

Convalescent Plasma Decreases Mortality for Non-Intubated Patients with Severe COVID-19

Based on a preliminary propensity score-matched control study, convalescent plasma is beneficial for non-intubated patients with severe COVID-19. At the…

May 27, 2020

Convalescent Plasma for COVID-19 Safe in First 5,000 Patients

With limited therapies for patients with COVID-19 and a mortality rate of approximately 50% for patients in the ICU, demand…

May 19, 2020

Coagulopathy in Patients with COVID-19—Interim Guidance from the International Society on Thrombosis and Haemostasis

Although the pathophysiology of severe COVID-19 is poorly understood, coagulopathy near the lungs has been shown to play an important…

May 13, 2020

SARS-CoV-2 Antibody Titers and Qualifying Donors for Convalescent Plasma

With no vetted therapies or vaccines for COVID-19 and almost a million confirmed cases in the United States alone, the…

April 29, 2020

Convalescent Plasma Donors Needed for COVID-19

Hospitals and blood collection centers are working with the US Government collaboratively to collect convalescent plasma from patients who have…

April 22, 2020

Tranexamic Acid Reduces Risk of Death in Patients with Traumatic Brain Injury

Globally, more than 60 million cases of traumatic brain injury occur annually, most of which are due to motor vehicle…

November 20, 2019

Platelet-Rich Plasma Is Superior to Platelets or Plasma for Wound Healing In Vitro

Wound healing is a multistep process involving many different types of cells, growth factors, and cytokines.  Platelets are key to…

November 6, 2019

Fibrinogen Concentrate Is Equivalent to Cryoprecipitate for Bleeding after Cardiac Surgery

Guidelines for the treatment of bleeding due to hypofibrinogenemia (fibrinogen level <1.5-2.0 g/L) after cardiac surgery recommend using either cryoprecipitate…

October 23, 2019

ABO Blood Group Alters Platelet Binding to von Willebrand Factor

Since individuals with type O blood have a lower risk of myocardial infarction, researchers hypothesized that the ABO blood group…

March 27, 2019

Increased Mortality and Blood Product Use in Trauma Patients with Hypothermia

About half of all trauma patients experience hypothermia (body temperature less than 36°C), which leads to coagulopathy and poor health…

March 12, 2019

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