Locus on Chromosome 5 Associated with Alloimmunization Red blood cell (RBC) transfusion remains the cornerstone for treating patients with sickle cell disease (SCD). While most patients with… January 9, 2019
Restrictive RBC Transfusions Safe for Patients Long-Term Several randomized clinical trials demonstrated restrictive RBC transfusion approaches are safe for patients over the short-term. Many patients with moderate… January 2, 2019
Whole Blood Transfusions on the Battlefield Uncontrolled hemorrhage is life threatening for trauma victims, and transfusion of blood products along with hemorrhage control is critical for… December 26, 2018
There’s an App for That: Detecting Anemia Using a Smartphone App Anemia affects more than 2 billion people worldwide, and a new smartphone app may help diagnose anemia using photos. Researchers… December 11, 2018
Evidence-Based Transfusion Guidelines Needed for Thalassemia Population Thalassemia is a hereditary hemolytic disease characterized by abnormal hemoglobin (Hb) production; the severity of the disease is based on… December 5, 2018
Older RBCs Associated with Increased Risk of Death Among Trauma Patients Current regulations allow red blood cells (RBCs) to be stored and used for up to 42 days. During this time,… November 27, 2018
Eculizumab for Treating Cold Agglutinin Disease Cold agglutinin disease (CAD) is a rare autoimmune disease caused by antibodies directed against red blood cell antigens, making them… October 24, 2018
Increased Risk of Myocardial Ischemia and Death in Severely Anemic Patients who Decline Transfusions Increased cardiac output can aid oxygen delivery in patients with mild anemia. When a critical hemoglobin (Hb) concentration is reached… October 10, 2018
Blood Collection and Processing Methods Affect Inflammatory Response in Vitro Numerous studies have examined whether storage time affects the safety and quality of red blood cells (RBCs), but few studies… October 3, 2018
Matching RH Genotypes for Patients with Sickle Cell Disease RH antigens are encoded by two highly polymorphic genes, RHD and RHCE. Homologous recombination and novel polymorphism have resulted in… September 19, 2018