Experimental Drug Voxelotor for Treatment of Patients with Sickle Cell Disease Results from a multicenter, randomized, clinical trial suggests that voxelotor, which inhibits sickle hemoglobin (HbS) polymerization, may be beneficial for… July 3, 2019
RBCs from Female Donors are Not Associated with Increased Mortality among Transfusion Recipients Plasma from female donors is associated with an increased risk of transfusion-related acute lung injury (TRALI). In order to investigate… June 19, 2019
RBC Transfusions Improve Quality of Life for Some Patients with Cancer Hematology and oncology outpatients often receive RBC transfusions to maintain critical hemoglobin (Hb) thresholds, but the impact of these transfusions… June 6, 2019
Delayed Hemolytic Transfusion Reactions are Under Diagnosed in Patients with Sickle Cell Disease Red blood cell transfusions are often used to treat patients with sickle cell disease (SCD), and these patients are at… May 1, 2019
Severe Trauma Patients Should Receive Pre-hospital Blood Products Severe trauma patients are at risk for hemorrhagic shock and death, and timely resuscitation is crucial for survival. The Prehospital… April 24, 2019
Increased Exogenous Compounds in RBCs after 42 Days of Storage Although morphological and biochemical storage lesions accumulate in stored red blood cells (RBCs), several recent randomized clinical trials have not… April 3, 2019
Recommendations for Patient Blood Management in Adults Since blood transfusions are one of the most common and most overused procedures in developed countries, patient blood management (PBM)… March 20, 2019
Increased Mortality and Blood Product Use in Trauma Patients with Hypothermia About half of all trauma patients experience hypothermia (body temperature less than 36°C), which leads to coagulopathy and poor health… March 12, 2019
Pathogen Reduction Technology Safe and Effective for Red Blood Cell Transfusions in Pediatric Patients with Cancer Pathogen reduction technology (PRT) is now commonly used to inactivate many types of pathogens in platelets and plasma. PRT for… February 27, 2019
Locus on Chromosome 5 Associated with Alloimmunization Red blood cell (RBC) transfusion remains the cornerstone for treating patients with sickle cell disease (SCD). While most patients with… January 9, 2019
RBC Transfusion