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RBC Transfusion

Experimental Drug Voxelotor for Treatment of Patients with Sickle Cell Disease

Results from a multicenter, randomized, clinical trial suggests that voxelotor, which inhibits sickle hemoglobin (HbS) polymerization, may be beneficial for…

July 3, 2019

RBCs from Female Donors are Not Associated with Increased Mortality among Transfusion Recipients

Plasma from female donors is associated with an increased risk of transfusion-related acute lung injury (TRALI). In order to investigate…

June 19, 2019

RBC Transfusions Improve Quality of Life for Some Patients with Cancer

Hematology and oncology outpatients often receive RBC transfusions to maintain critical hemoglobin (Hb) thresholds, but the impact of these transfusions…

June 6, 2019

Delayed Hemolytic Transfusion Reactions are Under Diagnosed in Patients with Sickle Cell Disease

Red blood cell transfusions are often used to treat patients with sickle cell disease (SCD), and these patients are at…

May 1, 2019

Severe Trauma Patients Should Receive Pre-hospital Blood Products

Severe trauma patients are at risk for hemorrhagic shock and death, and timely resuscitation is crucial for survival. The Prehospital…

April 24, 2019

Increased Exogenous Compounds in RBCs after 42 Days of Storage

Although morphological and biochemical storage lesions accumulate in stored red blood cells (RBCs), several recent randomized clinical trials have not…

April 3, 2019

Recommendations for Patient Blood Management in Adults

Since blood transfusions are one of the most common and most overused procedures in developed countries, patient blood management (PBM)…

March 20, 2019

Increased Mortality and Blood Product Use in Trauma Patients with Hypothermia

About half of all trauma patients experience hypothermia (body temperature less than 36°C), which leads to coagulopathy and poor health…

March 12, 2019

Pathogen Reduction Technology Safe and Effective for Red Blood Cell Transfusions in Pediatric Patients with Cancer

Pathogen reduction technology (PRT) is now commonly used to inactivate many types of pathogens in platelets and plasma.  PRT for…

February 27, 2019

Locus on Chromosome 5 Associated with Alloimmunization

Red blood cell (RBC) transfusion remains the cornerstone for treating patients with sickle cell disease (SCD). While most patients with…

January 9, 2019

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  • Storage Duration Affects Hematological and Metabolic Parameters in Patients with Sickle Cell Disease

  • Syphilis Infections Among US Blood Donors

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