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RBC Transfusion

Older RBCs Associated with Increased Risk of Death Among Trauma Patients

Current regulations allow red blood cells (RBCs) to be stored and used for up to 42 days. During this time,…

November 27, 2018

Eculizumab for Treating Cold Agglutinin Disease

Cold agglutinin disease (CAD) is a rare autoimmune disease caused by antibodies directed against red blood cell antigens, making them…

October 24, 2018

Increased Risk of Myocardial Ischemia and Death in Severely Anemic Patients who Decline Transfusions

Increased cardiac output can aid oxygen delivery in patients with mild anemia. When a critical hemoglobin (Hb) concentration is reached…

October 10, 2018

Blood Collection and Processing Methods Affect Inflammatory Response in Vitro

Numerous studies have examined whether storage time affects the safety and quality of red blood cells (RBCs), but few studies…

October 3, 2018

Matching RH Genotypes for Patients with Sickle Cell Disease

RH antigens are encoded by two highly polymorphic genes, RHD and RHCE.  Homologous recombination and novel polymorphism have resulted in…

September 19, 2018

Restrictive Transfusion Strategy for Cardiac Surgery Patients

Previous studies have reported that restrictive transfusion strategies are non-inferior compared to liberal strategies for cardiac surgery patients followed up…

August 30, 2018

Presence of Cell-free Nucleic Acids in Blood Products

Cell-free nucleic acids (CFNAs) are often present in plasma. A new study tested whether CFNAs are also present and active…

July 25, 2018

Behavior Modifications Support Changes to Restrictive RBC Transfusion Practices

Accumulating evidence supports restrictive RBC transfusion practices, and guidelines such as those recently released by the AABB recommend transfusing when…

June 27, 2018

Perioperative RBC Transfusions Linked to Increased Risk of Blood Clots

Venous thromboembolism (VTE) is associated with 5-10% of all hospital deaths, or about 100,000 to 200,000 deaths each year in…

June 20, 2018

Transfusion Dependence for Leukemia Patients Shortens Hospice Stay

Approximately 25,000 individuals in the United States die annually from leukemia. These individuals often require transfusions; however, hematologic oncologists have…

June 6, 2018

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