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Special Transfusion Situations

Intravenous Immunoglobulin Treatment for Patients with Heparin-Induced Thrombocytopenia Patients Unresponsive to Standard Treatment

Heparin-induced thrombocytopenia (HIT) is a severe complication of heparin treatment with significant risks of morbidity and mortality.  HIT is caused…

August 23, 2017

Low ADAMTS13 antigen and high ADAMTS13 antibody levels associated with mortality in TTP patients

While thrombotic thrombocytopenic purpura (TTP) has a mortality rate of approximately 10% even when treated, predictors of mortality are unknown. …

August 1, 2017

Systematic Review Recommends Standard Ratios of Blood Products for Massive Transfusion

Observational studies have suggested that higher ratios of plasma and platelets to red blood cells (RBCs) might lead to better…

July 26, 2017

Survival for Non-Trauma Patients Transfused with High Ratios of Plasma to Red Blood Cells

Although numerous studies have reported improved survival for trauma patients transfused with higher ratios of fresh frozen plasma (FFP) compared…

March 22, 2017

New PLASMIC Scoring System to Help Diagnose Thrombotic Thrombocytopenic Purpura

Thrombotic thrombocytopenic purpura (TTP) is a rare blood disorder caused by a lack of ADAMTS13 activity, which normally cleaves the…

March 8, 2017

Administration of Fibrinogen Concentrate during Cardiac Surgery Does Not Significantly Reduce Blood Loss

Since fibrinogen plays a key role in hemostasis and it is rapidly depleted during cardiac surgery, many cardiac surgeons give…

March 1, 2017

Postpartum Hemorrhage and Predelivery Anemia are Risk Factors for Severe Postpartum Anemia after Cesarean Sections

Cesarean sections are one of the most common surgical operations. Postpartum anemia is a prevalent side-effect, and has been linked…

February 1, 2017

Crizanlizumab May Help Sickle Cell Patients Prevent Pain Crises

Vaso-occlusive crisis—sickle cell pain related crisis—is the primary cause for hospital visits for sickle cell patients. Although the etiology of…

December 7, 2016

Drones Capable of Delivering Blood Products

Drones—small pilotless aircrafts—are capable of delivering packages cheaply and are not limited to passable roads or constrained by traffic. Rwanda…

November 22, 2016

Laboratory Testing is Suggested Before Intravenous Immunoglobulin is Given to Neonates

Although intravenous immunoglobulin (IVIG) use is documented to treat a wide range of severe disorders in adults, IVIG use in…

November 9, 2016

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