Acute Normovolemic Hemodilution Reduces Transfusions in Patients Undergoing Cardiac Surgery Approximately one to two million cardiac surgery operations are performed worldwide each year accounting for about 80% of all surgical… March 15, 2023
Increased Blood Use and Cost for Emergency Transfusions with Whole Blood Compared to Packed Red Blood Cells In the past two decades, a growing number of hospitals have started using whole blood to treat trauma patients and… February 16, 2023
Whole Blood and Survival in Adult Trauma Patients While blood component transfusions have been the standard of care for the past four decades, there is increasing interest in… January 25, 2023
Plasmapheresis Associated with Reduced Mortality Among Patients with Severe COVID-19 Over 6 million people have died due to COVID-19 worldwide since the start of the pandemic. Several comorbidities are associated… January 18, 2023
Sickle Cell Trait Testing of RBC Units While individuals with the sickle cell trait (SCT) have a single allele of hemoglobin S (HbS) and are eligible blood… December 27, 2022
HbS Promotes Proinflammatory Cytokine Production in Sickle Cell Disease Unlike patients with intravascular hemolysis without sickle cell disease (SCD) or those with β-thalassemia, patients with SCD have elevated baseline… November 9, 2022
Transfusion Thresholds for Patients Receiving ECMO Venovenous extracorporeal membrane oxygenation (ECMO) can be used to help provide respiratory support to patients with severe acute respiratory distress… November 2, 2022
Results from Phase 1 Trial for Artificial Hemoglobin Vesicles Advantages of artificial red blood cells (RBCs) include reduced risks of pathogens and alloimmunization and greater storage time compared to… August 24, 2022
Hypocalcemia Associated with Increased Transfusion Requirements in Pediatric Trauma Patients Hypocalcemia (Ca++ <1.1 mmol/L) has recently been identified as a fourth component of the “lethal triad” for mortality of adult… July 27, 2022
Guidelines for Hemolytic Disease of the Newborn Hemolytic disease of the newborn (HDN) is a serious disease associated with significant morbidity and mortality. HDN occurs when maternal… April 20, 2022
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