HbS Promotes Proinflammatory Cytokine Production in Sickle Cell Disease Unlike patients with intravascular hemolysis without sickle cell disease (SCD) or those with β-thalassemia, patients with SCD have elevated baseline… November 9, 2022
Transfusion Thresholds for Patients Receiving ECMO Venovenous extracorporeal membrane oxygenation (ECMO) can be used to help provide respiratory support to patients with severe acute respiratory distress… November 2, 2022
Results from Phase 1 Trial for Artificial Hemoglobin Vesicles Advantages of artificial red blood cells (RBCs) include reduced risks of pathogens and alloimmunization and greater storage time compared to… August 24, 2022
Hypocalcemia Associated with Increased Transfusion Requirements in Pediatric Trauma Patients Hypocalcemia (Ca++ <1.1 mmol/L) has recently been identified as a fourth component of the “lethal triad” for mortality of adult… July 27, 2022
Guidelines for Hemolytic Disease of the Newborn Hemolytic disease of the newborn (HDN) is a serious disease associated with significant morbidity and mortality. HDN occurs when maternal… April 20, 2022
Drone Delivery of Blood Products Faster in Rwanda and Reduces Wastage Over 75,000 units of blood components are transfused yearly in Rwanda, which is home to a population of approximately 13… March 30, 2022
Randomized Trial Show No Benefit for Pre-hospital Blood Transfusions in Patients with Severe Trauma Severe hemorrhage is the leading cause of death in trauma patients. In 2018, two randomized clinical trials showed contradictory results… March 15, 2022
Plasma Exchange for Hypertriglyceridemic Acute Pancreatitis Acute pancreatitis can be caused by many etiologies including high levels of plasma triglycerides. Hypertriglyceridemic acute pancreatitis (HTGAP) can cause… January 11, 2022
Platelet-Rich Plasma Injections Do Not Improve Ankle Osteoarthritis Ankle (tibiotalar) osteoarthritis affects approximately 3.4% of adults and is associated with a reduced quality of life. Effective non-surgical treatments… November 17, 2021
Benefits and Harms of Whole Blood versus Component Blood Transfusions Remain Unclear Transfusions may be in the form of whole blood (WB) or blood components (BC). Blood components include red blood cells,… November 9, 2021
Special Transfusion Situations