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Special Transfusion Situations

Guidelines for Hemolytic Disease of the Newborn

Hemolytic disease of the newborn (HDN) is a serious disease associated with significant morbidity and mortality.   HDN occurs when maternal…

April 20, 2022

Drone Delivery of Blood Products Faster in Rwanda and Reduces Wastage

Over 75,000 units of blood components are transfused yearly in Rwanda, which is home to a population of approximately 13…

March 30, 2022

Randomized Trial Show No Benefit for Pre-hospital Blood Transfusions in Patients with Severe Trauma

Severe hemorrhage is the leading cause of death in trauma patients.  In 2018, two randomized clinical trials showed contradictory results…

March 15, 2022

Plasma Exchange for Hypertriglyceridemic Acute Pancreatitis

Acute pancreatitis can be caused by many etiologies including high levels of plasma triglycerides.  Hypertriglyceridemic acute pancreatitis (HTGAP) can cause…

January 11, 2022

Platelet-Rich Plasma Injections Do Not Improve Ankle Osteoarthritis

Ankle (tibiotalar) osteoarthritis affects approximately 3.4% of adults and is associated with a reduced quality of life.  Effective non-surgical treatments…

November 17, 2021

Benefits and Harms of Whole Blood versus Component Blood Transfusions Remain Unclear

Transfusions may be in the form of whole blood (WB) or blood components (BC).  Blood components include red blood cells,…

November 9, 2021

Red Blood Cells May Act as Immune Sentinels

Anucleated red blood cells (RBCs) are essential for delivery of oxygen throughout the body but have been considered immunologically inert. …

November 1, 2021

Platelet-Rich Plasma Injections Do Not Reduce Tendon Dysfunction in Patients with Chronic Midportion Achilles Tendinopathy

Chronic midportion Achilles tendinopathy is caused by a breakdown of the cartilage in the middle of the Achilles tendon, resulting…

July 21, 2021

Plasma Exchange for Refractory Vaccine-Induced Immune Thrombotic Thrombocytopenia

Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a very rare side effect that can occur 5 to 30 days after immunization…

July 14, 2021

Gunshot Wounds Cause Significant Mortality, Blood Utilization, and Health Care Costs in the U.S.

Half of the world’s civilian firearms are owned by individuals in the United States.  The U.S. also leads all high-income…

July 6, 2021

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