Reducing Red Cell Use for Patients with Sickle Cell Disease during a Pandemic Since March 2020, the COVID-19 pandemic has strained blood inventories, so researchers at one Philadelphia hospital implemented new measures to… June 30, 2021
Population-Based Study in India Helps Refine Hemoglobin Thresholds for Anemia in Children Since hemoglobin thresholds for anemia are currently based on data collected over 50 years ago in Caucasian adults, the WHO… June 2, 2021
High Titer Convalescent Plasma Does Not Improve Survival of Hospitalized Patients with COVID-19 With few treatment options, more than 500,000 patients with COVID-19 were transfused with convalescent plasma in the United States. Observational… May 26, 2021
Tranexamic Acid To Reduce Blood Loss after Cesarean Delivery Tranexamic acid is a common antifibrinolytic drug used to prevent blood loss during surgeries and treat heavy menstrual cycles. Several… May 5, 2021
SARS-CoV-2 Preferentially Binds Blood Group A Expressed on Epithelial Cells Genome-wide studies and other observational studies have found an association between ABO(H) blood group and the likelihood of SARS-CoV-2 infection. … March 24, 2021
Early Convalescent Plasma Therapy Helps Prevent Severe COVID-19 COVID-19 convalescent plasma administered late in the course of disease has not shown clear benefits, but some studies suggest that… January 12, 2021
Serological Screening of Blood Donations Suggests SARS-CoV-2 May Have Been Introduced in the US before January 2020 The first case of SARS-Cov-2 in the United States was reported on January 19, 2020 in Washington State, but phylogenic… December 22, 2020
CRISPR-Cas9 Gene Editing and Lentiviral Gene Therapy Hold Promise to Treat Transfusion Dependent β-Globin Hemoglobinopathies Both transfusion-dependent β-thalassemia (TDT) and sickle cell disease (SCD) are common monogenetic diseases caused by mutations in the gene encoding… December 15, 2020
FDA Issues Emergency Use Authorization for SARS-CoV-2 Monoclonal Antibody Therapy Approximately 10% of COVID-19 cases lead to severe respiratory distress and hospitalization. In an effort to develop specific therapeutic options… November 17, 2020
Neutralizing Antibodies to SARS-CoV-2 Persist for at Least 5 Months Since December 2019, SARS-CoV-2 has infected over 46 million individuals worldwide leading to over 1 million deaths. While the majority… November 3, 2020
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