High Titer Convalescent Plasma Does Not Improve Survival of Hospitalized Patients with COVID-19 With few treatment options, more than 500,000 patients with COVID-19 were transfused with convalescent plasma in the United States. Observational… May 26, 2021
Tranexamic Acid To Reduce Blood Loss after Cesarean Delivery Tranexamic acid is a common antifibrinolytic drug used to prevent blood loss during surgeries and treat heavy menstrual cycles. Several… May 5, 2021
SARS-CoV-2 Preferentially Binds Blood Group A Expressed on Epithelial Cells Genome-wide studies and other observational studies have found an association between ABO(H) blood group and the likelihood of SARS-CoV-2 infection. … March 24, 2021
Early Convalescent Plasma Therapy Helps Prevent Severe COVID-19 COVID-19 convalescent plasma administered late in the course of disease has not shown clear benefits, but some studies suggest that… January 12, 2021
Serological Screening of Blood Donations Suggests SARS-CoV-2 May Have Been Introduced in the US before January 2020 The first case of SARS-Cov-2 in the United States was reported on January 19, 2020 in Washington State, but phylogenic… December 22, 2020
CRISPR-Cas9 Gene Editing and Lentiviral Gene Therapy Hold Promise to Treat Transfusion Dependent β-Globin Hemoglobinopathies Both transfusion-dependent β-thalassemia (TDT) and sickle cell disease (SCD) are common monogenetic diseases caused by mutations in the gene encoding… December 15, 2020
FDA Issues Emergency Use Authorization for SARS-CoV-2 Monoclonal Antibody Therapy Approximately 10% of COVID-19 cases lead to severe respiratory distress and hospitalization. In an effort to develop specific therapeutic options… November 17, 2020
Neutralizing Antibodies to SARS-CoV-2 Persist for at Least 5 Months Since December 2019, SARS-CoV-2 has infected over 46 million individuals worldwide leading to over 1 million deaths. While the majority… November 3, 2020
Cochrane Living Systematic Review: More Data Needed to Determine Efficacy of COVID-19 Convalescent Plasma Researchers from the Cochrane Library are performing monthly systematic reviews to evaluate the current data on the effectiveness of COVID-19… October 28, 2020
Meta-Analysis Examines Leukapheresis in Patients with Acute Myeloid Leukemia and Hyperleukocytosis Hyperleukocytosis (a white blood cell count greater than 100 X 109/L) is a medical emergency with a mortality rate up… October 14, 2020
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