Experimental Drug Voxelotor for Treatment of Patients with Sickle Cell Disease Results from a multicenter, randomized, clinical trial suggests that voxelotor, which inhibits sickle hemoglobin (HbS) polymerization, may be beneficial for… July 3, 2019
Drone Delivery of Blood Products in South Africa The South African National Blood Service (SANBS) in conjunction with the Western Cape Blood Service (WCBS) is preparing to test… June 12, 2019
Severe Trauma Patients Should Receive Pre-hospital Blood Products Severe trauma patients are at risk for hemorrhagic shock and death, and timely resuscitation is crucial for survival. The Prehospital… April 24, 2019
Increased Mortality and Blood Product Use in Trauma Patients with Hypothermia About half of all trauma patients experience hypothermia (body temperature less than 36°C), which leads to coagulopathy and poor health… March 12, 2019
Anti-CD47 Interference with Serological Testing Immunotherapy, the use of humanized monoclonal antibodies, is a promising therapy that works in conjunction with the patient’s own immune… February 6, 2019
A New Drug for Patients with Thrombotic Thrombocytopenic Purpura Thrombotic thrombocytopenic purpura (TTP) is a rare disease in which autoimmune antibodies target ADAMTS13, a protease that cleaves the… January 16, 2019
Whole Blood Transfusions on the Battlefield Uncontrolled hemorrhage is life threatening for trauma victims, and transfusion of blood products along with hemorrhage control is critical for… December 26, 2018
Older RBCs Associated with Increased Risk of Death Among Trauma Patients Current regulations allow red blood cells (RBCs) to be stored and used for up to 42 days. During this time,… November 27, 2018
Rituximab Treatment for Autoimmune Diseases Intravenous immune globin (IVIG) is used to treat immunoglobulin deficiency and autoimmune diseases. However, other immune-modulating drugs, such as… November 21, 2018
Eculizumab for Treating Cold Agglutinin Disease Cold agglutinin disease (CAD) is a rare autoimmune disease caused by antibodies directed against red blood cell antigens, making them… October 24, 2018
Special Transfusion Situations