Locally Transmitted Malaria in the United States Currently, half of the world’s population is at risk for malaria. Although malaria was endemic across the southern region of… October 15, 2025
Transfusion-related Alpha-Gal Syndrome Alpha-gal syndrome (AGS), first described in 2009, is associated with a tick bite in which exposed individuals develop IgE antibodies… August 13, 2025
Syphilis Infections Among US Blood Donors Syphilis is a sexually transmitted bacterial infection that may also be transmitted by transfusion. Active cases of syphilis are increasing… July 10, 2025
Babesia Infection Reduces Red Cell Deformability The United States reports the highest number of Babesia infections globally. Babesia, a tick-borne pathogen related to the malaria parasite,… May 14, 2025
No Transfusion-Transmission of Classic Creutzfeldt-Jakob Disease Classic Creutzfeldt-Jakob disease (CJD) is a rare and fatal neurodegenerative spongiform encephalopathy caused by prions (i.e., misfolded proteins). First recognized… July 17, 2024
National Surveillance for Unknown Transfusion-Transmitted Infections The prevention of transfusion-transmitted infections (TTI) is largely based on recruiting donors at low risk of being infected with a… March 13, 2024
A Possible Link between RBC Transfusions and Brain Amyloidosis? Cerebral amyloid angiopathy (CAA) has multiple etiologies but is characterized by deposits of misfolded amyloid β peptides and is the… September 20, 2023
Locally Acquired Malaria in Florida and Texas Malaria is a serious and potentially fatal disease that can be caused by five species of Plasmodium—P. falciparum, P. vivax,… July 5, 2023
Transfusion Transmission of Hepatitis A Virus during a Recent Epidemic in Europe In most infections of hepatitis A (HAV), individuals have very mild symptoms or are asymptomatic. Although rare in the U.S.,… February 21, 2023
SARS-CoV-2 RNA Frequently Found in Blood Donor Plasma is Not Infectious Although no cases of SARS-CoV-2 transfusion-transmission have been reported worldwide, RNA is detected in 15% to 90% of patients with… September 7, 2022
Transfusion Transmitted Infections