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Transfusion Transmitted Infections

Babesia Infection Reduces Red Cell Deformability

The United States reports the highest number of Babesia infections globally. Babesia, a tick-borne pathogen related to the malaria parasite,…

May 14, 2025

No Transfusion-Transmission of Classic Creutzfeldt-Jakob Disease

Classic Creutzfeldt-Jakob disease (CJD) is a rare and fatal neurodegenerative spongiform encephalopathy caused by prions (i.e., misfolded proteins). First recognized…

July 17, 2024

National Surveillance for Unknown Transfusion-Transmitted Infections

The prevention of transfusion-transmitted infections (TTI) is largely based on recruiting donors at low risk of being infected with a…

March 13, 2024

A Possible Link between RBC Transfusions and Brain Amyloidosis?

Cerebral amyloid angiopathy (CAA) has multiple etiologies but is characterized by deposits of misfolded amyloid β peptides and is the…

September 20, 2023

Locally Acquired Malaria in Florida and Texas

Malaria is a serious and potentially fatal disease that can be caused by five species of Plasmodium—P. falciparum, P. vivax,…

July 5, 2023

Transfusion Transmission of Hepatitis A Virus during a Recent Epidemic in Europe

In most infections of hepatitis A (HAV), individuals have very mild symptoms or are asymptomatic.  Although rare in the U.S.,…

February 21, 2023

SARS-CoV-2 RNA Frequently Found in Blood Donor Plasma is Not Infectious

Although no cases of SARS-CoV-2 transfusion-transmission have been reported worldwide, RNA is detected in 15% to 90% of patients with…

September 7, 2022

U.S. FDA Advises Blood Community Regarding Monkeypox Virus

The World Health Organization recently declared the current monkeypox epidemic a public health emergency.  First identified in laboratory monkeys in…

August 16, 2022

Updated FDA Guidance to Reduce Risk of Transmission of Creutzfeldt-Jakob Disease

The U.S. Food and Drug Administration (FDA) has issued updated guidance to reduce the transfusion-related transmission risk of Creutzfeldt-Jakob disease…

June 1, 2022

Tracking HIV Drug Resistance and Subtypes in Blood Donors

The risk of HIV transmission from blood transfusion is low (0.16 to 0.49 per million transfusions) but is still possible…

June 22, 2021

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  • Babesia Infection Reduces Red Cell Deformability

  • New Erythropoietin Gene Variants Linked to Hereditary Erythrocytosis

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