No Transfusion-Transmission of Classic Creutzfeldt-Jakob Disease Classic Creutzfeldt-Jakob disease (CJD) is a rare and fatal neurodegenerative spongiform encephalopathy caused by prions (i.e., misfolded proteins). First recognized… July 17, 2024
National Surveillance for Unknown Transfusion-Transmitted Infections The prevention of transfusion-transmitted infections (TTI) is largely based on recruiting donors at low risk of being infected with a… March 13, 2024
A Possible Link between RBC Transfusions and Brain Amyloidosis? Cerebral amyloid angiopathy (CAA) has multiple etiologies but is characterized by deposits of misfolded amyloid β peptides and is the… September 20, 2023
Locally Acquired Malaria in Florida and Texas Malaria is a serious and potentially fatal disease that can be caused by five species of Plasmodium—P. falciparum, P. vivax,… July 5, 2023
Transfusion Transmission of Hepatitis A Virus during a Recent Epidemic in Europe In most infections of hepatitis A (HAV), individuals have very mild symptoms or are asymptomatic. Although rare in the U.S.,… February 21, 2023
SARS-CoV-2 RNA Frequently Found in Blood Donor Plasma is Not Infectious Although no cases of SARS-CoV-2 transfusion-transmission have been reported worldwide, RNA is detected in 15% to 90% of patients with… September 7, 2022
U.S. FDA Advises Blood Community Regarding Monkeypox Virus The World Health Organization recently declared the current monkeypox epidemic a public health emergency. First identified in laboratory monkeys in… August 16, 2022
Updated FDA Guidance to Reduce Risk of Transmission of Creutzfeldt-Jakob Disease The U.S. Food and Drug Administration (FDA) has issued updated guidance to reduce the transfusion-related transmission risk of Creutzfeldt-Jakob disease… June 1, 2022
Tracking HIV Drug Resistance and Subtypes in Blood Donors The risk of HIV transmission from blood transfusion is low (0.16 to 0.49 per million transfusions) but is still possible… June 22, 2021
Screening for SARS-CoV-2 RNA in U.S. Blood Donors In March 2020, just a few months after the COVID-19 pandemic began in China, the U.S. launched the REDS Epidemiology,… June 8, 2021
Transfusion Transmitted Infections