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Archives for May–August 2021

Convalescent Plasma Does Not Prevent Disease Progression in COVID-19 Emergency Room Patients

Very few therapeutic options are available early in infectious disease epidemics with the exception of convalescent plasma.  In August 2020,…

August 24, 2021

SARS-CoV-2 Seropositivity of U.S. Blood Donors Prior to Availability of Vaccines

In the United States, blood collection organizations, including the American Red Cross (ARC), started testing all donations for antibodies to…

August 18, 2021

Mean Fluorescence Intensity to Select HLA-Matched Platelets

Over two million units of platelets are transfused each year in the United States—the majority to hematology-oncology patients.  Alloimmunization against…

August 13, 2021

U.S. National Platelet Inventory and Transfusion Practice Survey

Nearly 7,000 units of platelets are needed daily in the U.S., and platelet transfusions increased by 15.8% from 2017 to…

August 3, 2021

Pilot Randomized Clinical Trial Finds No Benefit for Prophylactic Plasma Transfusions

Annually, 2.4 million units of plasma are transfused in the U.S.  Approximately a quarter to half of plasma transfusions are…

July 27, 2021

Platelet-Rich Plasma Injections Do Not Reduce Tendon Dysfunction in Patients with Chronic Midportion Achilles Tendinopathy

Chronic midportion Achilles tendinopathy is caused by a breakdown of the cartilage in the middle of the Achilles tendon, resulting…

July 21, 2021

Plasma Exchange for Refractory Vaccine-Induced Immune Thrombotic Thrombocytopenia

Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a very rare side effect that can occur 5 to 30 days after immunization…

July 14, 2021

Gunshot Wounds Cause Significant Mortality, Blood Utilization, and Health Care Costs in the U.S.

Half of the world’s civilian firearms are owned by individuals in the United States.  The U.S. also leads all high-income…

July 6, 2021

Reducing Red Cell Use for Patients with Sickle Cell Disease during a Pandemic

Since March 2020, the COVID-19 pandemic has strained blood inventories, so researchers at one Philadelphia hospital implemented new measures to…

June 30, 2021

Tracking HIV Drug Resistance and Subtypes in Blood Donors

The risk of HIV transmission from blood transfusion is low (0.16 to 0.49 per million transfusions) but is still possible…

June 22, 2021

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