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Tranexamic Acid for Patients with Hematological Disorders

Patients with hematological disorders are often thrombocytopenic due to the pathology of their disease and/or treatment. Platelet transfusions, used both therapeutically and prophylactically, only reduce clinically significant bleeding episodes from 50% to 43% of patients, so other treatments are often needed. In 2016 the Cochrane Library published a review of tranexamic acid (TXA) and another lysine analog—epsilon aminocaproic acid—for the…

3 days ago

Interventions to Prevent Vasovagal Reactions among Blood Donors

  • Nipocalimab for Severe Hemolytic Disease of the Fetus and Newborn

  • Clinical Guidelines for Anemia and Chronic Kidney Disease

  • Ferritin-Guided Donation Policies Decrease Iron Deficiency

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  • RBC Transfusions to Treat Acute Heavy Menstrual Bleeding

  • RBC Transfusion Outcomes Similar in ICU Patients with and Without Cardiovascular Disease

  • Cryopreserved vs. Standard Platelets for Surgical Bleeding

  • Phosphatidylserine and Phosphatidylethanolamine Levels on RBCs Important for Transfusion Outcomes

  • Blood Donation and Improved Cardiometabolic Health

  • Mitochondrial DNA Acts as a “First Hit” for Antibody-Mediated TRALI

  • Liberal or Restrictive Transfusion Thresholds for Surgery Patients with High Cardiac Risk

  • Iron Supplementation for Blood Donors Based on Ferritin Levels

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