• Skip to main content
  • Skip to primary sidebar
Transfusion News
  • About Us
  • Topics
    • Adverse Events (non-infectious)
    • Blood Donation
    • Cell Therapy
    • Coagulation & Plasma Transfusion
    • Platelet Transfusion
    • Policy and Guidelines
    • Quality Control and Regulatory
    • RBC Transfusion
    • Serology/Genotyping
    • Special Transfusion Situations
    • Transfusion Transmitted Infections
  • Continuing Education
  • Archives
  • Podcasts
  • Question of the Day
  • Search
  • Subscribe to Email Alerts
  • Follow us on
  • Search
  • Subscribe to Email Alerts

Transfusion-Transmitted Malaria is Infrequent, Even in Malaria-Endemic Areas

May 24, 2013

A study among transfused patients in Ghana suggests that while malaria parasites are routinely detected in blood donations in malaria-endemic areas, transfusion-transmitted malaria (TTM) in these locations is uncommon. The study found that 68 (18.2%) of 372 patients with elevated risk of TTM received blood infected with Plasmodium falciparum, as detected by polymerase chain reaction (PCR). Among 50 of these patients who were further evaluated, only 7 (14%) became positive for P. falciparum by PCR during a 14-day post-transfusion period, and only 1 (2%) had genotypically-confirmed TTM. The research team also compared four malaria screening methods (microscopy, rapid diagnostic test, PCR, and enzyme immunoassay), concluding that none of these assays were sufficiently accurate and practical for routine use. In malaria-endemic areas, transfusion patients are often presumptively treated for malaria, and the World Health Organization currently recommends that all blood donations be screened for malaria. However, this study suggests that TTM may be relatively uncommon, and that TTM-related policy should be reevaluated.

Reference

1.    Owusu-Ofori AK, Betson M, Parry CM, Stothard JR, Bates I. Transfusion-Transmitted Malaria in Ghana. Clin Infect Dis 2013;56: 1735-41.

 

Filed Under

  • News
  • Transfusion Transmitted Infections

Recommended

  • High Variability in ICU Transfusion Practices Globally

  • Severe Anemia Is Associated with Necrotizing Enterocolitis, not RBC Transfusions

  • Red Cell Exchange for Patients with Sickle Cell Disease: an AABB Report

Show Comments

Comments on this article are closed.

Get the latest news. Subscribe to our mailing list. Sign Up

Primary Sidebar

Latest News

  • New Erythropoietin Gene Variants Linked to Hereditary Erythrocytosis

  • Multifaceted Threats to the Blood Supply from Climate Change

  • Distinct Roles for Differently Aged Platelets

  • Anemia Treatment Bundle Improves Hemoglobin Recovery after Critical Illness

    Question of the Day

    Copyright © 2025 John Wiley & Sons, Inc. All Rights Reserved.
    Privacy Policy

    Association for the Advancement of Blood and Biotherapies Wiley