RBCs Regulate Hemostasis Through Platelet-Dependent and -Independent Mechanisms Red blood cells (RBCs) deliver oxygen to tissues and also contribute to hemostasis and thrombosis through platelet interactions that promote… October 9, 2024
Liberal Transfusion Threshold of 9-10 g/dL for Patients with Myocardial Infarction While restrictive transfusion hemoglobin (Hb) thresholds are appropriate for most patients, those with anemia and myocardial infarction (MI) may benefit… October 2, 2024
Genetic Background of AnWj-Negative Blood Group Deciphered Of the 45 blood group systems comprising 362 described antigens, only a few high prevalence antigens are not genetically resolved… September 25, 2024
Donor-Specific Antibody Levels and Platelet Transfusion Response Among Refractory Patients Hematology-oncology patients often require multiple platelet transfusions, which can lead to immune-mediated platelet transfusion refractoriness. This condition may necessitate… September 19, 2024
Global Blood Supply Challenges The World Health Organization (WHO) considers blood an essential medicine, yet nearly two-thirds of countries—primarily low- and middle-income countries (LMIC)—lack… September 11, 2024
Prevalence and Trends of Maternal RBC Alloimmunization in the U.S. Maternal alloimmunization to RBC antigens, whether from blood transfusion or exposure to fetal antigens during pregnancy, can lead to hemolytic… September 4, 2024
Tranexamic Acid Does Not Reduce Bleeding or Transfusions in Patients Undergoing Liver Resection Tranexamic acid is a synthetic compound that prevents fibrin clot degradation and has been shown to reduce blood loss and… August 27, 2024
Blood Donation Rates Higher in Countries with Higher Healthcare Quality and Expenditure Most studies on blood donation rates have focused on individual donor behaviors, and little is known about how the quality… August 21, 2024
Nipocalimab Delays Intrauterine Transfusions for Severe Hemolytic Disease of the Fetus and Newborn Severe hemolytic disease of the fetus and newborn (HDFN) results from red blood cell (RBC) antigen incompatibility when IgG molecules… August 14, 2024
Monitoring Oxygen Saturation and Hemoglobin Values along with Iron and Erythropoietin Supplementation Reduces RBC Transfusion Frequency Approximately 20-40% of cardiac surgery patients have pre-operative anemia, and about half are transfused. Randomized controlled trials have shown intravenous… August 7, 2024
