• Skip to main content
  • Skip to primary sidebar
Transfusion News
  • About Us
  • Topics
    • Adverse Events (non-infectious)
    • Blood Donation
    • Cell Therapy
    • Coagulation & Plasma Transfusion
    • Platelet Transfusion
    • Policy and Guidelines
    • Quality Control and Regulatory
    • RBC Transfusion
    • Serology/Genotyping
    • Special Transfusion Situations
    • Transfusion Transmitted Infections
  • Continuing Education
  • Archives
  • Podcasts
  • Question of the Day
  • Search
  • Subscribe to Email Alerts
  • Follow us on
  • Search
  • Subscribe to Email Alerts

Better Screening Methods for Zika Virus Are Needed to Protect the Blood Supply

June 9, 2016

Conceptual image of the Zika virus.

 

As the Zika virus continues to spread, and evidence for its role in the pathophysiogy of microcephaly and Guillain-Barre continues to grow, understanding the natural history of the virus is paramount. Researchers at the Johns Hopkins University conducted a systematic literature review and pooled analysis of all publically available case reports of Zika infection. Only 20% of the 25 individuals with confirmed infection developed symptoms. On average, if symptoms appeared, they did so within 5.9 days (95% C.I., 4.4 to 7.6). Seroconversion occurred 9.0 days after infection (95% C.I., 7.0 to 11.6), and cases were viremic for 9.9 days (95% C.I., 6.8 to 21.4). In simulated calculations, screening blood donors for symptoms and the blood supply for antibody to Zika will only decrease the risk of transfusion-transmitted infections by 7% and 30%, respectively. Alternative methods such as direct virologic testing for Zika virus in areas with high incidence, and conservative deferrals of blood donors for travels to endemic areas, will likely be needed to ensure a safe blood supply.

Reference:

Lessler JT, Ott CT, Carcelen AC, Konikoff JM, Williamson J, Bi Q et al. Times to key events in the course of Zika infection and their implications: a systematic review and pooled analysis [Submitted]. Bull World Health Organ E-pub: 1 Apr 2016 doi: http://dx.doi.org/10.2471/BLT.16.174540

 

Filed Under

  • News
  • Quality Control and Regulatory
  • Transfusion Transmitted Infections

Recommended

  • ABO Blood Group Associated with COVID-19 Severity

  • Surveys Report Fewer Blood Collections and Transfusions in 2013

  • Intravenous vs Oral Iron for Pregnant Women in Africa

Show Comments

Comments on this article are closed.

Get the latest news. Subscribe to our mailing list. Sign Up

Primary Sidebar

Latest News

  • New Erythropoietin Gene Variants Linked to Hereditary Erythrocytosis

  • Multifaceted Threats to the Blood Supply from Climate Change

  • Distinct Roles for Differently Aged Platelets

  • Anemia Treatment Bundle Improves Hemoglobin Recovery after Critical Illness

    Question of the Day

    Copyright © 2025 John Wiley & Sons, Inc. All Rights Reserved.
    Privacy Policy

    Association for the Advancement of Blood and Biotherapies Wiley