Based on screening results of over 58 million blood donations from the American Red Cross from more than 14.7 million donors, the incidence, prevalence and residual risk for human immunodeficiency virus (HIV), hepatitis C virus (HCV) and hepatitis B virus (HBV) have remained steady or declined from 2007 to 2016. More than 88% (49.2 million) of the donations were from repeat donors, and the overall number of donations decreased by 25% during the 10-year study. Overall, 2.45 per 100,000 were positive for HIV, 19.45 per 100,000 for HCV, and 7.58 per 100,000 for HBV; prevalence decreased during the 10-year study by 38% for HIV, 30% for HBV, and 53% for HCV, but was only statistically significant for HCV. For 2015-2016, the overall donor prevalence was 1.65, 11.47, and 5.85 samples per 100,000 for HIV, HCV, and HBV, respectively. Although regional and ethnic variation was observed, prevalence of HIV, HCV and HBV was higher in one-time donors compared to repeat donors. Residual risk for HIV, HCV and HBV infection was one per 2.3 million, 2.6 million and 1.5 million donations, respectively. These data provide baseline infection rates to evaluate the impact of the new deferral policies for men who have sex with men made in December 2016 and other demographic changes to the U.S. population.
Reference:
