Mutating Haematopoietic Stem Cells May Cure Sickle Cell Disease Sickle cell disease and β-thalassaemia are caused by mutations in the β -globin gene. Previous studies have shown that transplants… November 16, 2016
Cord Blood Transplants Beneficial When Matched Donors Cannot Be Found The majority of patients in need of allogeneic hematopoietic cell-transplants do not have HLA-matched donors available. Researchers recently performed a… September 14, 2016
CAR-T Cell Cancer Therapies Hold Promise Chimeric antigen receptor (CAR)-T cell therapy harnesses the power of the patient’s own immune system to combat cancer. In theory,… June 22, 2016
Donor Weight Influences Bone Marrow Harvest Yield Although peripheral blood stem cells transplants have increased over the past few decades, bone marrow (BM) cells are still the… May 18, 2016
VIDEO: Viability of Hematopoietic Stem Cell Grafts Affects Clinical Outcomes Today we will be discussing allogeneic hematopoietic stem cell (or HSC) grafts, which are often used to treat patients with… October 14, 2015
Autologous CD8+ T Cells Inhibit Hematopoietic Progenitor Cell Mobilization but Enhance Engraftment The collection of sufficient autologous hematopoietic progenitor cells (HPCs) for bone marrow grafts does not always guarantee a successful engraftment. … August 7, 2015
VIDEO: Biosimilar Granulocyte-Colony-Stimulating Factor Today we will be discussing the biosimilar granulocyte -colony stimulating factor (or G-CSF ). G-CSF is currently used to treat and… February 15, 2015
Cell-Based Therapies and Treatment of Cardiac Disease Cardiac disease is the number one cause of death in the United States and Europe and costs health systems an… February 13, 2015
Double-Unit Cord-Blood Transplants Are Not Advantageous Compared to Single-Unit Transplants For over 20 years, umbilical-cord blood has been used in approximately 30,000 hematopoietic stem cell transplants for patients with severe… November 7, 2014
Most U.S. Patients are Likely to Find a Match for Hematopoietic Stem-Cell Transplants Hematopoietic stem-cell transplants (HSCT) from either cord blood or adult volunteer donors are often used to treat patients with blood… August 15, 2014
Cell Therapy