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Archive by Topic » CME

NT-proBNP Levels May Help Diagnose TACO and TRALI

Distinguishing between transfusion-associated circulatory overload (TACO), transfusion-related acute lung injury (TRALI), and other pulmonary transfusion reactions, including transfused-associated acute respiratory…

December 9, 2020

Platelet-Rich Plasma Is Superior to Platelets or Plasma for Wound Healing In Vitro

Wound healing is a multistep process involving many different types of cells, growth factors, and cytokines.  Platelets are key to…

November 6, 2019

Risk Factors for Hyperhemolysis Syndrome Identified

Hyperhemolysis Syndrome (HS) is a rare, potentially fatal condition characterized by the development of severe anemia after transfusion in which…

October 16, 2019

Immunogenicity of MMR Vaccine in Chronically Transfused Pediatric Patients

Both the American Advisory Committee on Immunization Practices (ACIP) and the Canadian immunization guide recommend delaying live vaccine immunizations for…

September 10, 2019

Red Blood Cells Donated by Smokers Associated with Lower Increments

Many recent studies have investigated the safety of blood according to donor demographics (e.g. age, sex, genetic polymorphisms) and blood…

August 14, 2019

RBC Alloimmunization is a Predictor of HLA Alloimmunization

Alloantibodies to the human leukocyte antigens (HLA) or red blood cells (RBCs) can develop after exposure to alloantigens such as…

July 17, 2019

RBC Transfusions Improve Quality of Life for Some Patients with Cancer

Hematology and oncology outpatients often receive RBC transfusions to maintain critical hemoglobin (Hb) thresholds, but the impact of these transfusions…

June 6, 2019

CRISPR-Gene Editing Uses for Transfusion Medicine

Clustered regularly interspaced short palindromic repeats (CRISPR) and Cas proteins evolved as part of the prokaryotes adaptive immune system. Cas…

April 18, 2019

Evidence-Based Transfusion Guidelines Needed for Thalassemia Population

Thalassemia is a hereditary hemolytic disease characterized by abnormal hemoglobin (Hb) production; the severity of the disease is based on…

December 5, 2018

Rituximab Treatment for Autoimmune Diseases

  Intravenous immune globin (IVIG) is used to treat immunoglobulin deficiency and autoimmune diseases.  However, other immune-modulating drugs, such as…

November 21, 2018

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