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Coagulation & Plasma Transfusion

Increased Mortality and Blood Product Use in Trauma Patients with Hypothermia

About half of all trauma patients experience hypothermia (body temperature less than 36°C), which leads to coagulopathy and poor health…

March 12, 2019

Management of Bleeding Episodes in Patients Taking Direct Oral Anticoagulants

Since 2012, direct oral anticoagulant (DOAC) use has increased as an alternative to oral anticoagulant agents such as warfarin to…

March 6, 2019

Emicizumab Therapy for Hemophilia A

Treatment for hemophilia A usually involves intravenous injections of factor VIII multiple times a week. In 2012, emicizumab (a bispecific…

September 5, 2018

Plasma Transfusions in Trauma Patients with Short Transport Times

Since the US Food and Drug Administration may soon approve freeze-dried or lyophilized plasma, several trials have recently investigated the…

August 9, 2018

Plasma Transfused During Transport to Hospital Saves Lives in Trauma Patients

  Nearly 50,000 Americans die from severe injuries each year, mainly from severe hemorrhage within two hours after the injury….

July 31, 2018

Presence of Cell-free Nucleic Acids in Blood Products

Cell-free nucleic acids (CFNAs) are often present in plasma. A new study tested whether CFNAs are also present and active…

July 25, 2018

Costs are High for Administrating Blood Transfusions

A recent micro-costing study in the United Kingdom suggests administration costs are high for blood transfusions. Researchers collected detailed data…

April 11, 2018

New Plasma Transfusion Guidelines from the British Society of Haematology

The British Society of Heamatology (BSH) recently published new guidelines for the use of fresh frozen plasma (FFP) and cryoprecipitate…

March 22, 2018

RBC and Plasma Transfusions Continue to Decline among US Hospitalizations

Based on data from the National Inpatient Sample from 1993 through 2014, hospitalized patients receiving at least one unit of…

February 27, 2018

Intrinsic Platelet Reactivity does not Affect Transfusion Outcome

Platelet reactivity to agonists has been shown to be different between donors yet consistent within the same individual. Researchers in…

July 20, 2017

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