Randomized Trial Results on Donor Sex and RBC Recipient Mortality Observational studies and systematic reviews have found conflicting results on the association between RBC donor sex and associated transfusion recipient… April 18, 2023
Whole Blood Derived Platelet vs. Apheresis Platelets During the COVID-19 pandemic, the U.S. experienced significant blood product shortages. In 2019, approximately 2.5 million platelet units were collected… April 12, 2023
Seven-Day Platelet Storage and Platelet Count Increments Platelets must be stored at room temperature to preserve function, which makes them susceptible to bacterial contamination. Recently, several countries… April 4, 2023
Prothrombin Complex Concentrate Increases Risk of Thromboembolic Events in Trauma Patients Four-factor prothrombin complex concentrate (4F-PCC) is a lyophilized concentrate of coagulation factors that is commonly used for urgent reversal of… March 29, 2023
FDA Guidance for COVID-19 Convalescent Plasma to Remain in Effect During the public health emergency for COVID-19, the U.S. Food and Drug Administration (FDA) issued guidance for the use of… March 22, 2023
Acute Normovolemic Hemodilution Reduces Transfusions in Patients Undergoing Cardiac Surgery Approximately one to two million cardiac surgery operations are performed worldwide each year accounting for about 80% of all surgical… March 15, 2023
Gene Therapy Phase 3 Study Results for Hemophilia B Hemophilia B is a rare, X-linked bleeding disorder caused by partial or complete deficiency of clotting factor IX. Currently, the… March 8, 2023
High Variability in Antibody Titer Determination in Transfusion Medicine Antibody levels are important for many aspects of clinical care from evaluating the incompatibility of transfusions and transplants to determining… March 2, 2023
Transfusion Transmission of Hepatitis A Virus during a Recent Epidemic in Europe In most infections of hepatitis A (HAV), individuals have very mild symptoms or are asymptomatic. Although rare in the U.S.,… February 21, 2023
Increased Blood Use and Cost for Emergency Transfusions with Whole Blood Compared to Packed Red Blood Cells In the past two decades, a growing number of hospitals have started using whole blood to treat trauma patients and… February 16, 2023