Cryopreserved Platelets for Functional Assays Both heparin-induced thrombocytopenia (HIT) and vaccine-induced immune thrombotic thrombocytopenia (VITT) are rare but serious drug reactions. HIT and VITT are… January 3, 2023
Sickle Cell Trait Testing of RBC Units While individuals with the sickle cell trait (SCT) have a single allele of hemoglobin S (HbS) and are eligible blood… December 27, 2022
Prothrombin Complex Concentrate Reduces RBC Transfusions during Cardiac Surgery Over one million people undergo complex cardiac surgeries worldwide each year. Cardiac surgeries carry a considerable risk of postoperative bleeding… December 21, 2022
Updated FDA Guidance to Reduce the Risk of Transfusion-Transmitted Malaria In April 2020, the U.S. Food and Drug Administration (FDA) issued four blood donor eligibility guidelines—including one for malaria—to help… December 13, 2022
First Autologous Human Transfusion of Engineered Platelets Approximately 2 million units of platelets are transfused each year in the United States, but there are many drawbacks and… December 7, 2022
Clinical Predictors of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT) Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a rare, life-threatening condition in pregnancy and is the leading cause of intracranial… November 30, 2022
Hypoxic Storage Helps to Preserve Red Blood Cells Red blood cells (RBCs) may be stored for up to 42 days, but over time storage lesions also develop. These… November 22, 2022
High-Titer Convalescent Plasma Increases Long-Term Survival for Patients with Severe COVID-19 Randomized controlled clinical trials have evaluated the safety and efficacy of COVID-19 convalescent plasma (CCP) and found high-titer CCP reduced… November 16, 2022
HbS Promotes Proinflammatory Cytokine Production in Sickle Cell Disease Unlike patients with intravascular hemolysis without sickle cell disease (SCD) or those with β-thalassemia, patients with SCD have elevated baseline… November 9, 2022
Transfusion Thresholds for Patients Receiving ECMO Venovenous extracorporeal membrane oxygenation (ECMO) can be used to help provide respiratory support to patients with severe acute respiratory distress… November 2, 2022
