Safety and Effectiveness of Tranexamic Acid in Cardiac Surgery Patients Tranexamic acid is an antifibrinolytic agent that is commonly used to control bleeding in patients undergoing cardiac surgery. Limited randomized… August 10, 2022
Racial Differences in Red Blood Cell Transfusions Transfusion guidelines recommend transfusing red blood cells (RBCs) when hemoglobin (Hb) levels drop below 7 or 8 g/dL, but variation… August 3, 2022
Hypocalcemia Associated with Increased Transfusion Requirements in Pediatric Trauma Patients Hypocalcemia (Ca++ <1.1 mmol/L) has recently been identified as a fourth component of the “lethal triad” for mortality of adult… July 27, 2022
New Alkaline Storage Solution Does Not Improve Post-Transfusion Recovery During storage, red blood cells (RBCs) develop metabolic and morphological “storage lesions.” The intracellular pH is an important variable that… July 20, 2022
Prothrombin Complex Concentrate for Complex Cardiac Surgery Patients Many cardiopulmonary bypass surgery patients with coagulopathy and bleeding require post-operative plasma transfusions. Instead of plasma, the off-label use of… July 14, 2022
Are WHO Guidelines for Serum Ferritin Levels for Female Blood Donors Too Low? The current World Health Organization (WHO) guidelines, based on expert opinion with low-grade evidence, define iron deficiency in healthy blood… July 6, 2022
Educational Materials Help to Retain Donors after a Temporary Deferral Previous studies have found that temporarily deferred donors sometimes believe that their deferral is permanent. In order to determine whether… June 29, 2022
Transfusion Guidelines for Major Hemorrhage Major hemorrhage is an emergency with significant morbidity and mortality. The British Society for Haematology (BSH) has updated transfusion guidelines… June 22, 2022
Donor-Recipient Sex and RBC Transfusion Outcomes Deferring plasma from multiparous females has dramatically reduced the incidence of antibody-mediated transfusion-related acute lung injury (TRALI). Some observational studies… June 14, 2022
Anti-CD19 CAR-T Cells as First-Line Therapy for High-Risk Large B-Cell Lymphoma Large-B-cell lymphoma (LBCL) is one of the most common types of non-Hodgkin lymphoma, and many patients do not respond well… June 7, 2022
