Anti-CD19 CAR-T Cells as First-Line Therapy for High-Risk Large B-Cell Lymphoma Large-B-cell lymphoma (LBCL) is one of the most common types of non-Hodgkin lymphoma, and many patients do not respond well… June 7, 2022
Updated FDA Guidance to Reduce Risk of Transmission of Creutzfeldt-Jakob Disease The U.S. Food and Drug Administration (FDA) has issued updated guidance to reduce the transfusion-related transmission risk of Creutzfeldt-Jakob disease… June 1, 2022
Genomic Profiles Associated with CAR T-Cell Therapy Efficacy Chimeric antigen receptor (CAR) T-cell therapy is a promising therapy used to treat hematological cancers by targeting a specific antigen. … May 24, 2022
Risk Factors for Allergic Transfusion Reactions in Pediatric Patients Allergic transfusion reactions (ATRs) are common and can range from mild to severe. Younger age, hematological/oncological disease, increasing number of… May 17, 2022
Target Trial Emulation Using Real World Data Suggest Older RBCs May Increase Mortality Data from many randomized clinical trials (RCTs) have not found an impact of storage time of red blood cells on… May 11, 2022
Tranexamic Acid in Noncardiac Surgeries Large randomized clinical trials have shown that tranexamic acid safely reduces bleeding in patients undergoing cardiac surgery or cesarean sections,… May 3, 2022
Perfluoroalkyl and Polyfluoroalkyl Levels after Blood Donations Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are ubiquitous synthetic compounds found in many products, including Teflon, water-resistant materials, paints, and firefighting… April 27, 2022
Guidelines for Hemolytic Disease of the Newborn Hemolytic disease of the newborn (HDN) is a serious disease associated with significant morbidity and mortality. HDN occurs when maternal… April 20, 2022
AABB Issues COVID-19 Convalescent Plasma Clinical Practice Guidelines The use of COVID-19 convalescent plasma (CCP) has been highly controversial since the beginning of the pandemic. With the Food… April 12, 2022
Transfusions with Whole Blood Compared to Packed Red Cells for African Children with Severe Anemia The World Health Organization (WHO) currently recommends that blood centers separate blood donations into components to maximize the number of… April 5, 2022