T helper Cells and Alloimmunization in Patients with Sickle Cell Disease Alloimmunization can lead to life-threatening hemolytic transfusion reactions and make it difficult to find compatible blood. While it is unknown… March 16, 2021
Increase in New Blood Donors during the COVID-19 Pandemic Blood donations increased, especially from new donors, during 9/11 in the U.S., recent bushfires in Australia, and other major crises. … March 10, 2021
Higher Donor Body Mass Index is Associated with Increased RBC Hemolysis Red blood cell (RBC) donor characteristics, collection, processing, storage, and transfusion have been well studied, but how the factors interact… March 3, 2021
Randomized Noninferiority Trial of Restrictive Transfusion Thresholds for Patients with Acute Myocardial Infarction Restrictive transfusion thresholds have been found to be beneficial for most patients. Anemia, however, is associated with poor outcomes in… February 24, 2021
Updated Guidance for COVID-19 Convalescent Plasma Use from the FDA and AABB With a lack of effective treatments for COVID-19, the U.S. FDA issued Emergency Use Authorization to use convalescent plasma to… February 17, 2021
Platelet Extracellular Vesicles Formed During Storage May Be Causative Agents in Non-Antibody-Mediated TRALI Transfusion-related acute lung-injury (TRALI) is a rare but potentially fatal complication of plasma transfusions affecting 1 in 10,000 transfusions and… February 9, 2021
Antigen Density on Surface of RBCs a Factor in RBC Clearance in Incompatible Transfusions Select patients with chronic anemia and sickle cell disease require recurrent transfusions and are at risk for alloimmunization and potentially… February 3, 2021
Epitope Matched HLA Platelets Are Noninferior to Standard Matched HLA Platelets Alloimmunization to human leukocyte antigens (HLA) leads to platelet refractoriness, defined as decreased post-transfusion platelet count increments (PCIs), and is… January 27, 2021
RHD Genotyping in Transfusion Practice Could Identify Novel RHD Alleles and Conserve D-negative Blood Partial D phenotypes (with altered D epitopes) and weak D phenotypes (with a reduced number of D antigens present on… January 20, 2021
Early Convalescent Plasma Therapy Helps Prevent Severe COVID-19 COVID-19 convalescent plasma administered late in the course of disease has not shown clear benefits, but some studies suggest that… January 12, 2021
