Epitope Matched HLA Platelets Are Noninferior to Standard Matched HLA Platelets Alloimmunization to human leukocyte antigens (HLA) leads to platelet refractoriness, defined as decreased post-transfusion platelet count increments (PCIs), and is… January 27, 2021
RHD Genotyping in Transfusion Practice Could Identify Novel RHD Alleles and Conserve D-negative Blood Partial D phenotypes (with altered D epitopes) and weak D phenotypes (with a reduced number of D antigens present on… January 20, 2021
Early Convalescent Plasma Therapy Helps Prevent Severe COVID-19 COVID-19 convalescent plasma administered late in the course of disease has not shown clear benefits, but some studies suggest that… January 12, 2021
Higher Hemoglobin Transfusion Thresholds Do Not Improve Outcomes in Preterm Infants Within the last decade, lower hemoglobin transfusion thresholds have been found to be safe and effective for most patient subpopulations. … January 5, 2021
Serological Screening of Blood Donations Suggests SARS-CoV-2 May Have Been Introduced in the US before January 2020 The first case of SARS-Cov-2 in the United States was reported on January 19, 2020 in Washington State, but phylogenic… December 22, 2020
CRISPR-Cas9 Gene Editing and Lentiviral Gene Therapy Hold Promise to Treat Transfusion Dependent β-Globin Hemoglobinopathies Both transfusion-dependent β-thalassemia (TDT) and sickle cell disease (SCD) are common monogenetic diseases caused by mutations in the gene encoding… December 15, 2020
NT-proBNP Levels May Help Diagnose TACO and TRALI Distinguishing between transfusion-associated circulatory overload (TACO), transfusion-related acute lung injury (TRALI), and other pulmonary transfusion reactions, including transfused-associated acute respiratory… December 9, 2020
RBC Transfusions Reduce Fatigability in Hospitalized Patients with Anemia In order to determine if red blood cell (RBC) transfusions improve quality of life for hospitalized patients with anemia, researchers… December 1, 2020
High Seroprevalence of SARS-CoV-2 in Kenyan Blood Donors As of late July 2020, only 3% of recorded deaths due to COVID-19 have occurred in Africa despite being home… November 25, 2020
FDA Issues Emergency Use Authorization for SARS-CoV-2 Monoclonal Antibody Therapy Approximately 10% of COVID-19 cases lead to severe respiratory distress and hospitalization. In an effort to develop specific therapeutic options… November 17, 2020
