CRISPR-Cas9 Gene Editing and Lentiviral Gene Therapy Hold Promise to Treat Transfusion Dependent β-Globin Hemoglobinopathies Both transfusion-dependent β-thalassemia (TDT) and sickle cell disease (SCD) are common monogenetic diseases caused by mutations in the gene encoding… December 15, 2020
NT-proBNP Levels May Help Diagnose TACO and TRALI Distinguishing between transfusion-associated circulatory overload (TACO), transfusion-related acute lung injury (TRALI), and other pulmonary transfusion reactions, including transfused-associated acute respiratory… December 9, 2020
RBC Transfusions Reduce Fatigability in Hospitalized Patients with Anemia In order to determine if red blood cell (RBC) transfusions improve quality of life for hospitalized patients with anemia, researchers… December 1, 2020
High Seroprevalence of SARS-CoV-2 in Kenyan Blood Donors As of late July 2020, only 3% of recorded deaths due to COVID-19 have occurred in Africa despite being home… November 25, 2020
FDA Issues Emergency Use Authorization for SARS-CoV-2 Monoclonal Antibody Therapy Approximately 10% of COVID-19 cases lead to severe respiratory distress and hospitalization. In an effort to develop specific therapeutic options… November 17, 2020
Transfusion-Transmission of Hepatitis E from Solvent/Detergent-Treated Plasma Scientists in France recently found evidence for possible hepatitis E virus (HEV) transmission in plasma treated with solvent/detergent from two… November 11, 2020
Neutralizing Antibodies to SARS-CoV-2 Persist for at Least 5 Months Since December 2019, SARS-CoV-2 has infected over 46 million individuals worldwide leading to over 1 million deaths. While the majority… November 3, 2020
Cochrane Living Systematic Review: More Data Needed to Determine Efficacy of COVID-19 Convalescent Plasma Researchers from the Cochrane Library are performing monthly systematic reviews to evaluate the current data on the effectiveness of COVID-19… October 28, 2020
No Evidence of SARS-CoV-2 Transfusion Transmission or Viral Infectivity About 20-25% of individuals infected with SARS-CoV-2 develop severe symptoms, but many infected individuals are asymptomatic and may donate blood… October 21, 2020
Meta-Analysis Examines Leukapheresis in Patients with Acute Myeloid Leukemia and Hyperleukocytosis Hyperleukocytosis (a white blood cell count greater than 100 X 109/L) is a medical emergency with a mortality rate up… October 14, 2020
