Plasma Exchange Does Not Reduce Risk of Death for Patients with Severe ANCA-Associated Vasculitis The underlying pathology behind antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is not clear; more effective and safer treatments are needed. High-dose… February 18, 2020
Final FDA Guidance to Reduce Transfusion-Transmitted Human T-Lymphotropic Virus Types I and II Transmission of the retroviruses human T-lymphotropic virus types I and II (HTLV-I/II) require cell-to-cell contact—mother to child transmission, sexual transmission,… February 12, 2020
New Draft Guidance Recommendations from the FDA to Reduce Risk of Transfusion-Transmitted Creutzfeldt-Jakob Diseases Creutzfeldt-Jakob Disease (CJD) is a fatal, rare neurological disease caused by infectious prions, or abnormally folded proteins. Sporadic CJD accounts… February 5, 2020
World on Heightened Alert for Novel Coronavirus Coronaviruses are a large family of enveloped RNA zoonotic viruses. The emerging novel coronavirus from Wuhan, China that was first… January 28, 2020
Erythropoietin Does Not Provide Neuroprotection in Preterm Infants In addition to stimulating red blood cell production, erythropoietin is a trophic factor in fetal brain development. Meta-analysis of four… January 22, 2020
New Drug, Enasidenib, Enhances Erythroid Differentiation and Lessens Anemia Enaisdenib inhibits isocitrate dehygrogenase 2 (IDH2)-mutant activity and was approved by the FDA in 2017 for patients with refractory or… January 15, 2020
Gene Therapy for Hemophilia A Decreases Bleeding Adeno-associated virus (AAV)-mediated gene therapy is a promising new treatment for hemophilia A which decreases bleeding and thus risk of… January 8, 2020
Platelet Transfusion Use in the United States Although RBC transfusions have decreased over the past decade, the demand for platelet transfusions has increased. In order to better… December 30, 2019
Mechanisms and Implications of Why Platelet Transfusions May Not Always Be Effective Platelet transfusions are not always effective at preventing bleeding in patients with inherited and acquired platelet disorders such as Glanzmann’s… December 18, 2019
Decreases in U.S. Blood Donors Despite Increases in Eligible Donors Although the number of RBC and whole blood cell transfusions has decreased by approximately 10% over the last decade, there… December 12, 2019
