RBC Alloimmunization is a Predictor of HLA Alloimmunization Alloantibodies to the human leukocyte antigens (HLA) or red blood cells (RBCs) can develop after exposure to alloantigens such as… July 17, 2019
The Role of Osteopontin in Murine TRALI Osteopontin (OPN) is a proinflammatory, multifunctional protein with both physiological and pathological roles. Since OPN attracts neutrophils, which are involved… July 11, 2019
Is there a Role for Liberal Transfusion Strategies? Based on data from more than 30 clinical trials, the AABB clinical practice guidelines recommend restrictive transfusion thresholds for hemodynamically… July 5, 2019
Experimental Drug Voxelotor for Treatment of Patients with Sickle Cell Disease Results from a multicenter, randomized, clinical trial suggests that voxelotor, which inhibits sickle hemoglobin (HbS) polymerization, may be beneficial for… July 3, 2019
Bacterial sepsis among transfusion recipients despite secondary mitigation strategies Bacterial contamination of platelet products is the most common transfusion-transmitted infection in the United States (U.S.). To mitigate this risk,… June 28, 2019
Enzymatic Conversion of Group A Blood to Universal Group O Blood As reported in Nature Microbiology, researchers have identified a set of enzymes isolated from human gut bacteria that convert the… June 26, 2019
RBCs from Female Donors are Not Associated with Increased Mortality among Transfusion Recipients Plasma from female donors is associated with an increased risk of transfusion-related acute lung injury (TRALI). In order to investigate… June 19, 2019
Drone Delivery of Blood Products in South Africa The South African National Blood Service (SANBS) in conjunction with the Western Cape Blood Service (WCBS) is preparing to test… June 12, 2019
RBC Transfusions Improve Quality of Life for Some Patients with Cancer Hematology and oncology outpatients often receive RBC transfusions to maintain critical hemoglobin (Hb) thresholds, but the impact of these transfusions… June 6, 2019
Screening Blood Donors for Familial Hypercholesterolemia Familial hypercholesterolemia (FH) a genetic disorder which increases the risk of cardiovascular disease 100-fold and affects approximately 1 in 250… May 29, 2019
