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Archive by Topic » News

Erythropoietin Does Not Provide Neuroprotection in Preterm Infants

In addition to stimulating red blood cell production, erythropoietin is a trophic factor in fetal brain development. Meta-analysis of four…

January 22, 2020

New Drug, Enasidenib, Enhances Erythroid Differentiation and Lessens Anemia

Enaisdenib inhibits isocitrate dehygrogenase 2 (IDH2)-mutant activity and was approved by the FDA in 2017 for patients with refractory or…

January 15, 2020

Gene Therapy for Hemophilia A Decreases Bleeding

Adeno-associated virus (AAV)-mediated gene therapy is a promising new treatment for hemophilia A which decreases bleeding and thus risk of…

January 8, 2020

Platelet Transfusion Use in the United States

Although RBC transfusions have decreased over the past decade, the demand for platelet transfusions has increased.   In order to better…

December 30, 2019

Mechanisms and Implications of Why Platelet Transfusions May Not Always Be Effective

Platelet transfusions are not always effective at preventing bleeding in patients with inherited and acquired platelet disorders such as Glanzmann’s…

December 18, 2019

Decreases in U.S. Blood Donors Despite Increases in Eligible Donors

Although the number of RBC and whole blood cell transfusions has decreased by approximately 10% over the last decade, there…

December 12, 2019

New Ebola Treatment Options Available

The current outbreak of Ebola virus disease (EVD) which began in August 2018 in North Kivu and Ituri provinces of…

December 3, 2019

Delayed Umbilical Cord for Cesarean Deliveries Does Not Increase Maternal Blood Loss

A 30 to 60 second delay in umbilical cord clamping for full-term and preterm neonates improves neonatal hemoglobin levels 24-48…

November 26, 2019

Tranexamic Acid Reduces Risk of Death in Patients with Traumatic Brain Injury

Globally, more than 60 million cases of traumatic brain injury occur annually, most of which are due to motor vehicle…

November 20, 2019

Large-Scale Production of Red Blood Cells from Peripheral Blood Mononuclear Cells

Cost-effective, large-scale production of red blood cells (RBCs) would eliminate blood shortages and ensure antigen-compatible cells are available for alloimunized…

November 13, 2019

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  • RBC Transfusions in Neonatal ICUs Above Restrictive Hb Thresholds

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