Large-Scale Production of Red Blood Cells from Peripheral Blood Mononuclear Cells Cost-effective, large-scale production of red blood cells (RBCs) would eliminate blood shortages and ensure antigen-compatible cells are available for alloimunized… November 13, 2019
Platelet-Rich Plasma Is Superior to Platelets or Plasma for Wound Healing In Vitro Wound healing is a multistep process involving many different types of cells, growth factors, and cytokines. Platelets are key to… November 6, 2019
Urgent Global Need of Blood Products The current World Health Organization (WHO) guidelines recommend 10-20 blood donations per 1000 individuals, but these guidelines do not take… October 29, 2019
Thrombosomes (Lyophilized Platelets) Appear Safe in Phase 1 Trial Data from a phase 1, open-label, multi-center safety trial of lyophilized platelets were recently presented at the 2019 AABB… October 24, 2019
Fibrinogen Concentrate Is Equivalent to Cryoprecipitate for Bleeding after Cardiac Surgery Guidelines for the treatment of bleeding due to hypofibrinogenemia (fibrinogen level <1.5-2.0 g/L) after cardiac surgery recommend using either cryoprecipitate… October 23, 2019
Risk Factors for Hyperhemolysis Syndrome Identified Hyperhemolysis Syndrome (HS) is a rare, potentially fatal condition characterized by the development of severe anemia after transfusion in which… October 16, 2019
FDA Guidance to Control for Bacterial Contamination in Platelets The U.S. Food and Drug Administration (FDA) has issued final guidance to reduce bacterial contamination of platelets stored at room… October 9, 2019
Donor, Blood Component, and Patient Factors all Affect Hemoglobin Levels after RBC Transfusion To better understand the interplay between donor characteristics, blood product preparation and storage, and patient characteristics on the outcome of… October 2, 2019
Extended Trial Confirms that Frequent Donors Give More Blood but Are More Likely to be Iron Deficient The original INTERVAL trial randomly assigned more than 45,000 blood donors in the United Kingdom to different donation frequencies… September 25, 2019
Blood Transfusions in Space Although no major hemorrhages or blood transfusions have occurred in space and the risk is low, transfusions for astronauts on… September 18, 2019
