Apheresis Lymphocyte Collections for CAR-T Cell Production Usually Well Tolerated By Cancer Patients Production of chimeric antigen receptor (CAR) T-cells involve genetically modifying the patient’s own T-cells, and these cells have been shown… May 17, 2017
Higher Hematocrit Levels Are Associated with Increased Thrombosis Risk and Reduced Bleeding A growing number of recent studies have observed an association between elevated hematocrit levels and thrombosis. However, the mechanism behind… May 10, 2017
Early Administration of Tranexamic Acid Reduces Maternal Deaths Due to Bleeding Administration of tranexamic acid, an antifibrinolytic drug, has been shown to reduce bleeding in trauma and surgery patients. The results… May 3, 2017
Transfusion of Red Blood Cells from Younger Donors Is Not Associated with Improved Survival Animal models suggest that blood from younger donors may provide revitalizing benefits, but findings from observational cohort studies on this… April 26, 2017
Stored Whole Blood Treated with Pathogen Reduction Acceptable for Transfusion Pathogen reduction technology (PRT) hold promise for eliminating many known and emerging pathogens in donated blood and thus preventing transfusion… April 19, 2017
Prophylactic Platelet Transfusions are Not Superior to Supportive Care for Dengue Patients with Thrombocytopenia According to the World Health Organization, the incidence of dengue has increased 30-fold in the past 50 years, and over… April 12, 2017
Current Evidence Suggests that Non-invasive Procedures are Best to Treat Fetal and Neonatal Alloimmune Thrombocytopenia Fetal and neonatal alloimmune thrombocytopenia (FNAIT) occurs when maternal alloantibodies develop against fetal platelet antigens. FNAIT may cause severe bleeding… April 5, 2017
Large-Scale Iron Testing Feasible for Blood Centers Iron deficiency is a common problem among frequent blood donors. The Canadian Blood Services recently sought to identify donors at… March 29, 2017
Survival for Non-Trauma Patients Transfused with High Ratios of Plasma to Red Blood Cells Although numerous studies have reported improved survival for trauma patients transfused with higher ratios of fresh frozen plasma (FFP) compared… March 22, 2017
Liquid Plasma Acceptable for Severe Trauma Patients with Major Bleeding Recent studies have highlighted the importance of expeditious transfusion of plasma, platelets and red blood cells in a 1:1:1 ratio… March 16, 2017
