Tranexamic Acid Does Not Reduce Bleeding or Transfusions in Patients with Hematological Malignancies Prophylactic platelet transfusions are common for patients with hematological malignancies and severe hypoproliferative thrombocytopenia. Tranexamic acid, an antifibrinolytic drug, has… January 30, 2025
New FDA Draft Guidance to Reduce Transfusion-Transmitted Malaria Malaria, caused by five Plasmodium species (e.g., P. falciparum), is recognized as a significant transfusion-transmitted infection by the U.S. Food… January 22, 2025
A New, Simple Proxy to Measure Oxygen Unloading and the Quality of Stored Blood The functional quality of transfused blood depends upon oxygen delivery to the tissues. Oxygen carrying capacity is easily and routinely… January 16, 2025
Hypovolemic Phlebotomy Reduces Transfusions During Liver Surgery About 15% to 20% of patients undergoing liver resections require RBC transfusions. Current guidelines propose a number of options to… January 8, 2025
Phase 1 Trial Results for Lentiviral Gene Therapy for Patients with Hemophilia A Hemophilia A is a X-linked disorder characterized by less than 1% of blood clotting Factor VIII in the blood and… January 1, 2025
Duffy-Null-Associated Neutrophil Counts in Oncology Patients with Febrile Neutropenia Duffy negativity is common in Sub-Saharan Africa and the Arabian Peninsula, and approximately 70% of self-identified Black individuals in the… December 26, 2024
Liberal versus Restrictive Transfusion Thresholds for Patients with Subarachnoid Hemorrhage Aneurysmal subarachnoid hemorrhages may result in severe neurological problems with fatality rates reaching as high as 67%, particularly in patients… December 17, 2024
Blood Cell Salvage Decreases Transfusions After Decannulation from Extracorporeal Membrane Oxygenation (ECMO) Veno-venous extracorporeal membrane oxygenation (VV-ECMO) supportive therapy improves outcomes and reduces mortality for patients with acute respiratory distress syndrome. VV-ECMO,… December 10, 2024
Quality and Effectiveness of Irradiated Platelets Platelets are often irradiated to inactivate residual lymphocytes and prevent transfusion-associated graft-vs-host disease. As irradiated platelets are widely used, researchers… December 5, 2024
Multi-Country Review of ABO-Incompatible Red Blood Cell Transfusions Safety measures to prevent ABO-incompatible red blood cell (RBC) transfusions are in place throughout the entire process from blood donation… November 26, 2024
