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Archive by Topic » News

Platelet-RBC Complexes Associated with RBC Clearance

Platelet-RBC (P-RBC) complexes are associated with several diseases such as sickle cell disease, malaria, and immune thrombocytopenia.  Since diseased RBCs…

February 21, 2024

MiPLATE Clinical Trial: Mirasol® Pathogen Reduction Treated Platelets

The Mirasol® Pathogen Reduction Technology System (Terumo, BCT, Lakewood, CO) uses a combination of riboflavin (vitamin B2) and UV light…

February 13, 2024

Platelet Transfusions and Increased Risk of Death or Neurodevelopmental Impairment in Preterm Infants

Preterm infants are at an increased risk for intracranial hemorrhage, as many are thrombocytopenic (<150,000 platelets/µL). Although there is little…

February 7, 2024

The Genealogy of Blood Cells

Hematopoietic stem cells (HSCs) give rise to all types of blood cells through myeloid progenitor cell types (e.g., red blood…

January 31, 2024

Pathogenesis of Antibody-Mediated TRALI by Complement

Transfusion-related acute lung injury (TRALI) is a rare, life-threatening adverse transfusion reaction that is difficult to predict and treat. The…

January 25, 2024

Prediction of Vasovagal Reactions in Whole Blood Donors Using a Scoring System

Previous studies have identified risk factors for vasovagal reactions (VVRs) in blood donors, including young age, female sex, lower body…

January 17, 2024

Deep Learning A.I. System for Platelet Management

Platelet inventory management is challenging due to their short shelf-life and fluctuating demand.  Researchers in Germany created a risk assessment…

January 10, 2024

Low Alloimmunization Risk if No Antibodies Formed during First 20 RBC Transfused Units

RBC transfusions are critical for many patients with sickle cell disease.  Patients are at risk, however, of developing alloantibodies, which…

January 4, 2024

Thalidomide Reduces Bleeding and Blood Transfusions in Patients with Small-Intestinal Angiodysplasia

Small-intestinal angiodysplasia (SIA), characterized by vascular malformation in the GI tract, is the most common cause of recurrent bleeding in…

December 27, 2023

Variability of Blood Donor Incentives Globally

Although the WHO recommends that blood collection establishments (BCEs) rely on voluntary, non-remunerated donations, a new study recently published by…

December 20, 2023

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