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Archive by Topic » News

Pathogenesis of Antibody-Mediated TRALI by Complement

Transfusion-related acute lung injury (TRALI) is a rare, life-threatening adverse transfusion reaction that is difficult to predict and treat. The…

January 25, 2024

Prediction of Vasovagal Reactions in Whole Blood Donors Using a Scoring System

Previous studies have identified risk factors for vasovagal reactions (VVRs) in blood donors, including young age, female sex, lower body…

January 17, 2024

Deep Learning A.I. System for Platelet Management

Platelet inventory management is challenging due to their short shelf-life and fluctuating demand.  Researchers in Germany created a risk assessment…

January 10, 2024

Low Alloimmunization Risk if No Antibodies Formed during First 20 RBC Transfused Units

RBC transfusions are critical for many patients with sickle cell disease.  Patients are at risk, however, of developing alloantibodies, which…

January 4, 2024

Thalidomide Reduces Bleeding and Blood Transfusions in Patients with Small-Intestinal Angiodysplasia

Small-intestinal angiodysplasia (SIA), characterized by vascular malformation in the GI tract, is the most common cause of recurrent bleeding in…

December 27, 2023

Variability of Blood Donor Incentives Globally

Although the WHO recommends that blood collection establishments (BCEs) rely on voluntary, non-remunerated donations, a new study recently published by…

December 20, 2023

Safety of Platelet and Plasma Transfusions in the COVID-19 Era

By September 2022, 96% of U.S. blood donors had antibodies to SARS-CoV-2 due to infection and/or vaccination.  Some patient advocacy…

December 13, 2023

Darbepoetin Alfa Reduces RBC Transfusions in Infants with HDFN Treated with Intrauterine Transfusions

Hemolytic disease of the fetus and newborn (HDFN) is a severe disorder caused by maternal antibodies against fetal RBC antigens…

December 6, 2023

Novel Technology-Enabled Personalized Nomogram Increases Plasma Yield from Donations

Beginning in 1992, the U.S. has used a standard weight-based nomogram to guide appropriate plasma collection targets—15% to 42% of…

November 29, 2023

Frequent Platelet Donation and Risk for T-cell Lymphopenia

In the United States, over 90% of platelets are collected by plateletpheresis, and donors may give platelets up to 24…

November 22, 2023

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