Low Hematocrit and Bleeding Risk for Patients with Hypoproliferative Thrombocytopenia Prophylactic platelet transfusions are the standard of care for hypoproliferative thrombocytopenia. Over one thousand adult patients (n=1077) enrolled in a… September 13, 2017
Leukoreduction of Platelet Units Followed by Mirasol Pathogen Reduction May Prevent Alloimmunization Alloimmunization to donor platelets is common in transfused, immunosuppressed oncology patients. Leukoreduction reduces alloimmunization by more than half. Researchers recently… August 30, 2017
Gram-positive Bacterial Contamination of Platelets a Concern In a study recently published in TRANSFUSION, researchers from the Canadian Blood Services reported results from routine and quality control… July 6, 2017
Higher Hematocrit Levels Are Associated with Increased Thrombosis Risk and Reduced Bleeding A growing number of recent studies have observed an association between elevated hematocrit levels and thrombosis. However, the mechanism behind… May 10, 2017
Prophylactic Platelet Transfusions are Not Superior to Supportive Care for Dengue Patients with Thrombocytopenia According to the World Health Organization, the incidence of dengue has increased 30-fold in the past 50 years, and over… April 12, 2017
Current Evidence Suggests that Non-invasive Procedures are Best to Treat Fetal and Neonatal Alloimmune Thrombocytopenia Fetal and neonatal alloimmune thrombocytopenia (FNAIT) occurs when maternal alloantibodies develop against fetal platelet antigens. FNAIT may cause severe bleeding… April 5, 2017
Platelet transfusions are not recommended to treat cerebral hemorrhage for patients taking antiplatelet therapy Spontaneous intracerebral hemorrhages are often serious and may be fatal. Platelet transfusions are used to treat patients with hemorrhagic… May 26, 2016
T cell Mediated Platelet Refractoriness Patients who are refractory to platelet transfusion are a challenge for transfusion services. Platelet refractoriness has historically been attributed to… April 13, 2016
Cryopreserved Platelets are Hemostatically Functional in Vitro Inventory and storage of cryopreserved platelets (CPP) would be simple in comparison to platelets that are normally stored at room… March 23, 2016
Acid-Treated Platelets May Be an Alternative to HLA-Matched Platelets for Transfusions HLA antibodies can lead to patients becoming refractory to platelet transfusions, and transfusions can be difficult when HLA-matched donors cannot… February 24, 2016
Platelet Transfusion