RBC and Plasma Transfusions Decreased in the U.S. (2015-2018) Blood transfusions are one of the most common medical procedures in hospitalized patients, and robust data from randomized clinical trials… September 28, 2021
REDS-III Study Highlights Need for Pediatric Oncology Transfusion Guidelines Pediatric hematology/oncology patients receive a significant proportion of pediatric transfusions. Data, however, are limited guiding clinical decisions for transfusions… September 22, 2021
Transfusion Outcomes in Very-Low-Birth Weight Infants Associated with Donor Sex and Age Blood donor characteristics may affect transfusion outcomes, but data are conflicting. In order to investigate the association of donor sex… September 15, 2021
Gunshot Wounds Cause Significant Mortality, Blood Utilization, and Health Care Costs in the U.S. Half of the world’s civilian firearms are owned by individuals in the United States. The U.S. also leads all high-income… July 6, 2021
Population-Based Study in India Helps Refine Hemoglobin Thresholds for Anemia in Children Since hemoglobin thresholds for anemia are currently based on data collected over 50 years ago in Caucasian adults, the WHO… June 2, 2021
RBCs with “Storage Lesions” Are Rapidly Cleared From Circulation and Impact Transfusion Recovery The ability to store red blood cells (RBC) up to 42 days ensures a stable blood supply, and several randomized… May 12, 2021
Sutimlimab, a Monoclonal Antibody, to Treat Cold Agglutinin Disease Cold agglutinin disease is a rare autoimmune hemolytic anemia that affects 12 per million individuals and is caused by IgM… April 13, 2021
42-Day Old RBCs Deliver Oxygen as Well as 7-Day Old RBCs Many studies have investigated the physiological, biochemical, and structural abnormalities that RBCs acquire during storage, but few have managed to… March 29, 2021
Higher Donor Body Mass Index is Associated with Increased RBC Hemolysis Red blood cell (RBC) donor characteristics, collection, processing, storage, and transfusion have been well studied, but how the factors interact… March 3, 2021
Randomized Noninferiority Trial of Restrictive Transfusion Thresholds for Patients with Acute Myocardial Infarction Restrictive transfusion thresholds have been found to be beneficial for most patients. Anemia, however, is associated with poor outcomes in… February 24, 2021