Sex-Matched Transfusions May Reduce Mortality While plasma from female donors increases the risk of transfusion-related acute lung injury (TRALI), observational studies have had conflicting results… October 6, 2022
Mitapivat Trial Results in Adults with Pyruvate Kinase Deficiency Requiring Transfusions Pyruvate kinase deficiency is a rare, congenital form of chronic hemolytic anemia. Current treatments for pyruvate kinase deficiency, including RBC… August 31, 2022
Results from Phase 1 Trial for Artificial Hemoglobin Vesicles Advantages of artificial red blood cells (RBCs) include reduced risks of pathogens and alloimmunization and greater storage time compared to… August 24, 2022
Safety and Effectiveness of Tranexamic Acid in Cardiac Surgery Patients Tranexamic acid is an antifibrinolytic agent that is commonly used to control bleeding in patients undergoing cardiac surgery. Limited randomized… August 10, 2022
Racial Differences in Red Blood Cell Transfusions Transfusion guidelines recommend transfusing red blood cells (RBCs) when hemoglobin (Hb) levels drop below 7 or 8 g/dL, but variation… August 3, 2022
Hypocalcemia Associated with Increased Transfusion Requirements in Pediatric Trauma Patients Hypocalcemia (Ca++ <1.1 mmol/L) has recently been identified as a fourth component of the “lethal triad” for mortality of adult… July 27, 2022
New Alkaline Storage Solution Does Not Improve Post-Transfusion Recovery During storage, red blood cells (RBCs) develop metabolic and morphological “storage lesions.” The intracellular pH is an important variable that… July 20, 2022
Donor-Recipient Sex and RBC Transfusion Outcomes Deferring plasma from multiparous females has dramatically reduced the incidence of antibody-mediated transfusion-related acute lung injury (TRALI). Some observational studies… June 14, 2022
Target Trial Emulation Using Real World Data Suggest Older RBCs May Increase Mortality Data from many randomized clinical trials (RCTs) have not found an impact of storage time of red blood cells on… May 11, 2022
Transfusions with Whole Blood Compared to Packed Red Cells for African Children with Severe Anemia The World Health Organization (WHO) currently recommends that blood centers separate blood donations into components to maximize the number of… April 5, 2022
RBC Transfusion