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RBC Transfusion

Hypocalcemia Associated with Increased Transfusion Requirements in Pediatric Trauma Patients

Hypocalcemia (Ca++ <1.1 mmol/L) has recently been identified as a fourth component of the “lethal triad” for mortality of adult…

July 27, 2022

New Alkaline Storage Solution Does Not Improve Post-Transfusion Recovery

During storage, red blood cells (RBCs) develop metabolic and morphological “storage lesions.”  The intracellular pH is an important variable that…

July 20, 2022

Donor-Recipient Sex and RBC Transfusion Outcomes

Deferring plasma from multiparous females has dramatically reduced the incidence of antibody-mediated transfusion-related acute lung injury (TRALI).  Some observational studies…

June 14, 2022

Target Trial Emulation Using Real World Data Suggest Older RBCs May Increase Mortality

Data from many randomized clinical trials (RCTs) have not found an impact of storage time of red blood cells on…

May 11, 2022

Transfusions with Whole Blood Compared to Packed Red Cells for African Children with Severe Anemia

The World Health Organization (WHO) currently recommends that blood centers separate blood donations into components to maximize the number of…

April 5, 2022

Drone Delivery of Blood Products Faster in Rwanda and Reduces Wastage

Over 75,000 units of blood components are transfused yearly in Rwanda, which is home to a population of approximately 13…

March 30, 2022

Randomized Trial Show No Benefit for Pre-hospital Blood Transfusions in Patients with Severe Trauma

Severe hemorrhage is the leading cause of death in trauma patients.  In 2018, two randomized clinical trials showed contradictory results…

March 15, 2022

Updated Transfusion Guidelines for High-Risk Surgery Patients

Patient blood management programs use a multimodal approach to conserve blood and simultaneously improve patient outcomes.  Transfusion guidelines are central…

February 16, 2022

Machine Learning-Based Algorithm to Predict Intraoperative RBC Use during Cardiothoracic Surgery

Cardiothoracic surgery patients have a high risk for hemorrhage and occasionally require massive transfusions, though most patients require 0 to…

February 9, 2022

Variable Transfusion Practices for Bleeding ICU Patients Globally

Approximately 40-50% of patients in the intensive care unit (ICU) receive blood transfusions.  Many studies have focused on bleeding in…

January 19, 2022

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