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RBC Transfusion

Stabilization of Blood Collection and Use in the United States

Since 1997, the biennial National Blood Collection and Utilization Survey (NBCUS) has been collecting data on blood use and collection…

May 2, 2023

Randomized Trial Results on Donor Sex and RBC Recipient Mortality

Observational studies and systematic reviews have found conflicting results on the association between RBC donor sex and associated transfusion recipient…

April 18, 2023

Acute Normovolemic Hemodilution Reduces Transfusions in Patients Undergoing Cardiac Surgery

Approximately one to two million cardiac surgery operations are performed worldwide each year accounting for about 80% of all surgical…

March 15, 2023

Increased Blood Use and Cost for Emergency Transfusions with Whole Blood Compared to Packed Red Blood Cells

In the past two decades, a growing number of hospitals have started using whole blood to treat trauma patients and…

February 16, 2023

Thromboelastometry and Clinical Guidance for Fibrinogen Infusions during Liver Transplantation

Thromboelastometry provides individualized measures of clot kinetics and structure, and has played an increasingly important role in the management of…

February 8, 2023

Sickle Cell Trait Testing of RBC Units

While individuals with the sickle cell trait (SCT) have a single allele of hemoglobin S (HbS) and are eligible blood…

December 27, 2022

Hypoxic Storage Helps to Preserve Red Blood Cells

Red blood cells (RBCs) may be stored for up to 42 days, but over time storage lesions also develop.  These…

November 22, 2022

Transfusion Thresholds for Patients Receiving ECMO

Venovenous extracorporeal membrane oxygenation (ECMO) can be used to help provide respiratory support to patients with severe acute respiratory distress…

November 2, 2022

Sex-Matched Transfusions May Reduce Mortality

While plasma from female donors increases the risk of transfusion-related acute lung injury (TRALI), observational studies have had conflicting results…

October 6, 2022

Mitapivat Trial Results in Adults with Pyruvate Kinase Deficiency Requiring Transfusions

Pyruvate kinase deficiency is a rare, congenital form of chronic hemolytic anemia.  Current treatments for pyruvate kinase deficiency, including RBC…

August 31, 2022

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Latest News

  • Gene Editing of HBG1 and HBG2 Promotors to Treat β-Thalassemia and Sickle Cell Disease

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