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RBC Transfusion

REDS-III Study Highlights Need for Pediatric Oncology Transfusion Guidelines

  Pediatric hematology/oncology patients receive a significant proportion of pediatric transfusions.  Data, however, are limited guiding clinical decisions for transfusions…

September 22, 2021

Transfusion Outcomes in Very-Low-Birth Weight Infants Associated with Donor Sex and Age

Blood donor characteristics may affect transfusion outcomes, but data are conflicting.  In order to investigate the association of donor sex…

September 15, 2021

Gunshot Wounds Cause Significant Mortality, Blood Utilization, and Health Care Costs in the U.S.

Half of the world’s civilian firearms are owned by individuals in the United States.  The U.S. also leads all high-income…

July 6, 2021

Population-Based Study in India Helps Refine Hemoglobin Thresholds for Anemia in Children

Since hemoglobin thresholds for anemia are currently based on data collected over 50 years ago in Caucasian adults, the WHO…

June 2, 2021

RBCs with “Storage Lesions” Are Rapidly Cleared From Circulation and Impact Transfusion Recovery

The ability to store red blood cells (RBC) up to 42 days ensures a stable blood supply, and several randomized…

May 12, 2021

Sutimlimab, a Monoclonal Antibody, to Treat Cold Agglutinin Disease

Cold agglutinin disease is a rare autoimmune hemolytic anemia that affects 12 per million individuals and is caused by IgM…

April 13, 2021

42-Day Old RBCs Deliver Oxygen as Well as 7-Day Old RBCs

Many studies have investigated the physiological, biochemical, and structural abnormalities that RBCs acquire during storage, but few have managed to…

March 29, 2021

Higher Donor Body Mass Index is Associated with Increased RBC Hemolysis

Red blood cell (RBC) donor characteristics, collection, processing, storage, and transfusion have been well studied, but how the factors interact…

March 3, 2021

Randomized Noninferiority Trial of Restrictive Transfusion Thresholds for Patients with Acute Myocardial Infarction

Restrictive transfusion thresholds have been found to be beneficial for most patients.  Anemia, however, is associated with poor outcomes in…

February 24, 2021

Higher Hemoglobin Transfusion Thresholds Do Not Improve Outcomes in Preterm Infants

Within the last decade, lower hemoglobin transfusion thresholds have been found to be safe and effective for most patient subpopulations. …

January 5, 2021

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