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Special Transfusion Situations

Artificial Intelligence to Predict Immunogenicity of Amino Acid Substitutions of Blood Group Antigens

Of the approximately 400 RBC blood group antigens, only ABO/D are matched for routine transfusions. Some RBC blood group antigens…

August 20, 2025

Transfusion-related Alpha-Gal Syndrome

Alpha-gal syndrome (AGS), first described in 2009, is associated with a tick bite in which exposed individuals develop IgE antibodies…

August 13, 2025

Blood Transfusion Strategies for Major Trauma

Early transfusion is associated with reduced morbidity and mortality in major bleeding trauma events. However, the optimal mix of blood…

July 22, 2025

Babesia Infection Reduces Red Cell Deformability

The United States reports the highest number of Babesia infections globally. Babesia, a tick-borne pathogen related to the malaria parasite,…

May 14, 2025

New Erythropoietin Gene Variants Linked to Hereditary Erythrocytosis

Erythrocytosis, a condition marked by the overproduction of red blood cells (RBCs), can be either congenital or acquired. Erythropoietin (EPO),…

May 7, 2025

Anemia Treatment Bundle Improves Hemoglobin Recovery after Critical Illness

Very few studies have examined how anemia management strategies affect post-hospitalization outcomes for critically ill patients. A recent randomized controlled…

April 16, 2025

Traditional Chinese Herbs Not Effective for Intracerebral Hemorrhage: A Randomized Trial

Herbs have been used in traditional Chinese medicine for centuries, but the effectiveness of many of these treatments remain unknown….

February 6, 2025

Duffy-Null-Associated Neutrophil Counts in Oncology Patients with Febrile Neutropenia

Duffy negativity is common in Sub-Saharan Africa and the Arabian Peninsula, and approximately 70% of self-identified Black individuals in the…

December 26, 2024

Prevalence and Trends of Maternal RBC Alloimmunization in the U.S.

Maternal alloimmunization to RBC antigens, whether from blood transfusion or exposure to fetal antigens during pregnancy, can lead to hemolytic…

September 4, 2024

Nipocalimab Delays Intrauterine Transfusions for Severe Hemolytic Disease of the Fetus and Newborn

Severe hemolytic disease of the fetus and newborn (HDFN) results from red blood cell (RBC) antigen incompatibility when IgG molecules…

August 14, 2024

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Latest News

  • Artificial Intelligence to Predict Immunogenicity of Amino Acid Substitutions of Blood Group Antigens

  • Transfusion-related Alpha-Gal Syndrome

  • 2024 Serious Hazards of Transfusions (SHOT) Report in the U.K.

  • Machine Learning Model for Estimating Perioperative Transfusion Risks

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