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Special Transfusion Situations

Rituximab Treatment for Autoimmune Diseases

  Intravenous immune globin (IVIG) is used to treat immunoglobulin deficiency and autoimmune diseases.  However, other immune-modulating drugs, such as…

November 21, 2018

Eculizumab for Treating Cold Agglutinin Disease

Cold agglutinin disease (CAD) is a rare autoimmune disease caused by antibodies directed against red blood cell antigens, making them…

October 24, 2018

Red Cell Exchange for Patients with Sickle Cell Disease: an AABB Report

The Therapeutic Apheresis Subsection of the AABB, composed of 15 practicing apheresis physicians from 14 institutions, recently summarized how they…

September 12, 2018

Emicizumab Therapy for Hemophilia A

Treatment for hemophilia A usually involves intravenous injections of factor VIII multiple times a week. In 2012, emicizumab (a bispecific…

September 5, 2018

Plasma Transfusions in Trauma Patients with Short Transport Times

Since the US Food and Drug Administration may soon approve freeze-dried or lyophilized plasma, several trials have recently investigated the…

August 9, 2018

Plasma Transfused During Transport to Hospital Saves Lives in Trauma Patients

  Nearly 50,000 Americans die from severe injuries each year, mainly from severe hemorrhage within two hours after the injury….

July 31, 2018

Transfusion Dependence for Leukemia Patients Shortens Hospice Stay

Approximately 25,000 individuals in the United States die annually from leukemia. These individuals often require transfusions; however, hematologic oncologists have…

June 6, 2018

WBC Alloimmunization Infrequent in Granulocyte Transfusions

Neutropenia is characterized by abnormally low counts of neutrophils and is a common condition among patients receiving chemotherapy or hematopoietic…

May 16, 2018

Rapid Transfusions after Combat Causalities Improves Chances of Survival

Since bleeding is a major cause of death in combat causalities and civilian trauma cases, researchers recently examined the association…

November 1, 2017

Patients with Moderate ADAMTS13 Deficiency have Increased Risk of Dying

Thrombotic microangiopathies (TMAs) may develop from diverse group of etiologies. While activity levels less than 10% of ADAMTS13 help to…

September 21, 2017

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