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Archives for January–April 2019

Severe Trauma Patients Should Receive Pre-hospital Blood Products

Severe trauma patients are at risk for hemorrhagic shock and death, and timely resuscitation is crucial for survival. The Prehospital…

April 24, 2019

CRISPR-Gene Editing Uses for Transfusion Medicine

Clustered regularly interspaced short palindromic repeats (CRISPR) and Cas proteins evolved as part of the prokaryotes adaptive immune system. Cas…

April 18, 2019

Chagas Disease Screening for Family Members of Positive Blood Donors

Chagas disease (CD) is a zoonotic infection caused by blood sucking Trypanosoma cruzi—a parasite that infects over 6 million people…

April 10, 2019

Increased Exogenous Compounds in RBCs after 42 Days of Storage

Although morphological and biochemical storage lesions accumulate in stored red blood cells (RBCs), several recent randomized clinical trials have not…

April 3, 2019

ABO Blood Group Alters Platelet Binding to von Willebrand Factor

Since individuals with type O blood have a lower risk of myocardial infarction, researchers hypothesized that the ABO blood group…

March 27, 2019

Recommendations for Patient Blood Management in Adults

Since blood transfusions are one of the most common and most overused procedures in developed countries, patient blood management (PBM)…

March 20, 2019

Increased Mortality and Blood Product Use in Trauma Patients with Hypothermia

About half of all trauma patients experience hypothermia (body temperature less than 36°C), which leads to coagulopathy and poor health…

March 12, 2019

Management of Bleeding Episodes in Patients Taking Direct Oral Anticoagulants

Since 2012, direct oral anticoagulant (DOAC) use has increased as an alternative to oral anticoagulant agents such as warfarin to…

March 6, 2019

Pathogen Reduction Technology Safe and Effective for Red Blood Cell Transfusions in Pediatric Patients with Cancer

Pathogen reduction technology (PRT) is now commonly used to inactivate many types of pathogens in platelets and plasma.  PRT for…

February 27, 2019

Female Blood Donors at Risk for Iron Deficiency

In the United States, adolescents 16-18 years old donate approximately 1.5 million units of blood each year. Although donating blood…

February 21, 2019

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