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Archives for January–April 2019

Frequent Platelet Donors at Risk for Lymphopenia

In the US, the vast majority of platelets are collected via apheresis. Individuals may donate apheresis-derived platelets up to 24…

February 13, 2019

Anti-CD47 Interference with Serological Testing

Immunotherapy, the use of humanized monoclonal antibodies, is a promising therapy that works in conjunction with the patient’s own immune…

February 6, 2019

Babesia and Bacterial Contamination Most Frequent Transfusion-Transmitted Infections

Based on hemovigilance data from the National Healthcare Safety Network (NHSN), viral transfusion-transmitted infections (TTI) are rare while bacterial contamination…

January 30, 2019

Teenage Blood Donors at Increased Risk for Iron Deficiency

Teenagers (16-18 years of age) contribute 10% of the blood supply in the United States. Teenagers require iron to grow…

January 23, 2019

A New Drug for Patients with Thrombotic Thrombocytopenic Purpura

  Thrombotic thrombocytopenic purpura (TTP) is a rare disease in which autoimmune antibodies target ADAMTS13, a protease that cleaves the…

January 16, 2019

Locus on Chromosome 5 Associated with Alloimmunization

Red blood cell (RBC) transfusion remains the cornerstone for treating patients with sickle cell disease (SCD). While most patients with…

January 9, 2019

Restrictive RBC Transfusions Safe for Patients Long-Term

Several randomized clinical trials demonstrated restrictive RBC transfusion approaches are safe for patients over the short-term. Many patients with moderate…

January 2, 2019

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  • New Erythropoietin Gene Variants Linked to Hereditary Erythrocytosis

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