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Archives for January–April 2020

Minimal Residual Risk for HIV, Hepatitis B, and Hepatitis C from Blood Products

Based on screening results of over 58 million blood donations from the American Red Cross from more than 14.7 million…

February 28, 2020

Plasma Exchange Does Not Reduce Risk of Death for Patients with Severe ANCA-Associated Vasculitis

The underlying pathology behind antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is not clear; more effective and safer treatments are needed.  High-dose…

February 18, 2020

Final FDA Guidance to Reduce Transfusion-Transmitted Human T-Lymphotropic Virus Types I and II

Transmission of the retroviruses human T-lymphotropic virus types I and II (HTLV-I/II) require cell-to-cell contact—mother to child transmission, sexual transmission,…

February 12, 2020

New Draft Guidance Recommendations from the FDA to Reduce Risk of Transfusion-Transmitted Creutzfeldt-Jakob Diseases

Creutzfeldt-Jakob Disease (CJD) is a fatal, rare neurological disease caused by infectious prions, or abnormally folded proteins.  Sporadic CJD accounts…

February 5, 2020

World on Heightened Alert for Novel Coronavirus

Coronaviruses are a large family of enveloped RNA zoonotic viruses. The emerging novel coronavirus from Wuhan, China that was first…

January 28, 2020

Erythropoietin Does Not Provide Neuroprotection in Preterm Infants

In addition to stimulating red blood cell production, erythropoietin is a trophic factor in fetal brain development. Meta-analysis of four…

January 22, 2020

New Drug, Enasidenib, Enhances Erythroid Differentiation and Lessens Anemia

Enaisdenib inhibits isocitrate dehygrogenase 2 (IDH2)-mutant activity and was approved by the FDA in 2017 for patients with refractory or…

January 15, 2020

Gene Therapy for Hemophilia A Decreases Bleeding

Adeno-associated virus (AAV)-mediated gene therapy is a promising new treatment for hemophilia A which decreases bleeding and thus risk of…

January 8, 2020

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