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Archives for May–August 2021

HLA Induced Refractoriness to Platelet Transfusions

Platelet transfusion refractoriness (PTR) is usually caused by non-immune platelet consumption but can also be caused by immune-mediated platelet destruction. …

June 16, 2021

Screening for SARS-CoV-2 RNA in U.S. Blood Donors

In March 2020, just a few months after the COVID-19 pandemic began in China, the U.S. launched the REDS Epidemiology,…

June 8, 2021

Population-Based Study in India Helps Refine Hemoglobin Thresholds for Anemia in Children

Since hemoglobin thresholds for anemia are currently based on data collected over 50 years ago in Caucasian adults, the WHO…

June 2, 2021

High Titer Convalescent Plasma Does Not Improve Survival of Hospitalized Patients with COVID-19

With few treatment options, more than 500,000 patients with COVID-19 were transfused with convalescent plasma in the United States.  Observational…

May 26, 2021

ABO-incompatible Platelet Transfusions and Platelet Recovery in Patients with Intracerebral Hemorrhage

Historically, standard practice has been to provide ABO-compatible platelets when possible.  However, since hemolysis is rare after single platelet transfusions…

May 18, 2021

RBCs with “Storage Lesions” Are Rapidly Cleared From Circulation and Impact Transfusion Recovery

The ability to store red blood cells (RBC) up to 42 days ensures a stable blood supply, and several randomized…

May 12, 2021

Tranexamic Acid To Reduce Blood Loss after Cesarean Delivery

Tranexamic acid is a common antifibrinolytic drug used to prevent blood loss during surgeries and treat heavy menstrual cycles.  Several…

May 5, 2021

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