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Archives for May–August 2024

Tranexamic Acid Does Not Reduce Bleeding or Transfusions in Patients Undergoing Liver Resection

Tranexamic acid is a synthetic compound that prevents fibrin clot degradation and has been shown to reduce blood loss and…

August 27, 2024

Blood Donation Rates Higher in Countries with Higher Healthcare Quality and Expenditure

Most studies on blood donation rates have focused on individual donor behaviors, and little is known about how the quality…

August 21, 2024

Nipocalimab Delays Intrauterine Transfusions for Severe Hemolytic Disease of the Fetus and Newborn

Severe hemolytic disease of the fetus and newborn (HDFN) results from red blood cell (RBC) antigen incompatibility when IgG molecules…

August 14, 2024

Monitoring Oxygen Saturation and Hemoglobin Values along with Iron and Erythropoietin Supplementation Reduces RBC Transfusion Frequency

Approximately 20-40% of cardiac surgery patients have pre-operative anemia, and about half are transfused. Randomized controlled trials have shown intravenous…

August 7, 2024

Updated FDA Guidance for Blood Donor Eligibility for Blood Pressure and Pulse

The U.S. Food and Drug Administration (FDA) has previously provided guidance for the eligibility of blood donors with blood pressure…

July 30, 2024

Carnitine Metabolism Associated with Red Blood Cell Hemolysis

Red blood cells can be stored up to 42 days, after which they progressively develop a series of storage lesions—partly…

July 25, 2024

No Transfusion-Transmission of Classic Creutzfeldt-Jakob Disease

Classic Creutzfeldt-Jakob disease (CJD) is a rare and fatal neurodegenerative spongiform encephalopathy caused by prions (i.e., misfolded proteins). First recognized…

July 17, 2024

RBC Transfusions Guidelines for Very Preterm Infants

Most clinical practice guidelines for blood transfusion have focused on adults and limited recommendations are available for children and neonates….

July 9, 2024

Ferritin-Guided Blood Donations Protect Iron Stores in Donors

In both North America and Europe, whole blood donors are eligible to donate whole blood every 56 days. Donors lose…

July 3, 2024

Donor Deferral Model Evaluates Impact of New Individual Risk Assessment

When AIDS emerged in the early 1980s, the risk of acquiring HIV from a transfusion was approximately 1.1%. The U.S….

June 28, 2024

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